Gene: SLC9A9
Official Full Name: solute carrier family 9 member A9provided by HGNC
Gene Summary: This gene encodes a sodium/proton exchanger that is a member of the solute carrier 9 protein family. The encoded protein localizes the to the late recycling endosomes and may play an important role in maintaining cation homeostasis. Mutations in this gene are associated with autism susceptibility 16 and attention-deficit/hyperactivity disorder. [provided by RefSeq, Mar 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00281 | SLC9A9 Knockout cell line (HeLa) | Human | SLC9A9 | 1:3~1:6 | Negative | Online Inquiry |
SLC9A9 Gene Knockout Cell Lines are specialized cellular models designed to facilitate the investigation of the SLC9A9 gene, which encodes a sodium-hydrogen exchanger critical for cellular ion homeostasis. By utilizing CRISPR-Cas9 gene editing technology, these knockout cell lines effectively disable the SLC9A9 gene, enabling scientists to study the resulting phenotypic changes and physiological implications of reduced protein function. These models provide insights into the role of SLC9A9 in various biological processes, including intracellular pH regulation, drug transport, and cellular signaling pathways.
The primary function of SLC9A9 involves the management of sodium and hydrogen ion concentrations across the cellular membrane, thereby influencing numerous metabolic and signaling pathways. By creating knockout variants, researchers can analyze how the absence of this gene affects cellular behavior, including proliferation, differentiation, and responses to pharmacological agents. This is particularly significant in studying conditions such as cancer, neurodegenerative diseases, and metabolic disorders, where ion dysregulation may play a pivotal role.
In both research and clinical settings, SLC9A9 Gene Knockout Cell Lines have emerged as valuable tools that enable tailored investigations into specific pathways influenced by ion transport mechanisms. Their utility extends to drug development, where understanding the interactions and consequences of SLC9A9 modulation fosters the identification of novel therapeutic targets.
What sets our SLC9A9 Gene Knockout Cell Lines apart from alternatives is their precise genetic engineering through state-of-the-art CRISPR technology, ensuring high specificity and reliability in experimental outcomes. Furthermore, they are backed by a comprehensive library of analytical resources and technical support, enhancing the research experience.
For researchers and clinicians alike, these knockout cell lines represent a significant advancement in biological research, providing a platform for elucidating complex cellular processes and paving the way for innovative therapeutic solutions. Our company prides itself on its extensive expertise in genetic technologies and its commitment to delivering high-quality cellular models that empower the scientific community in their endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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