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SLC39A10 Knockout Cell Lines

Gene: SLC39A10

Official Full Name: solute carrier family 39 member 10provided by HGNC

Gene Summary: Zinc is an essential cofactor for hundreds of enzymes. It is involved in protein, nucleic acid, carbohydrate, and lipid metabolism, as well as in the control of gene transcription, growth, development, and differentiation. SLC39A10 belongs to a subfamily of proteins that show structural characteristics of zinc transporters (Taylor and Nicholson, 2003 [PubMed 12659941]).[supplied by OMIM, Mar 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO13996 SLC39A10 Knockout cell line (HeLa) Human SLC39A10 1:3~1:6 Negative Online Inquiry
KO13997 SLC39A10 Knockout cell line (HCT 116) Human SLC39A10 1:2~1:4 Negative Online Inquiry
KO13998 SLC39A10 Knockout cell line (HEK293) Human SLC39A10 1:3~1:6 Negative Online Inquiry
KO13999 SLC39A10 Knockout cell line (A549) Human SLC39A10 1:3~1:4 Negative Online Inquiry

Background

SLC39A10 Gene Knockout Cell Lines are specialized cell lines genetically engineered to lack the SLC39A10 gene, which encodes a zinc transporter implicated in various physiological processes, including cellular zinc homeostasis and signaling pathways. By eliminating the expression of this gene, researchers can study the functional consequences of disrupted zinc transport, providing insights into cellular metabolism and the role of zinc in health and disease.

These cell lines exhibit altered mechanisms of zinc uptake and regulation, enabling researchers to investigate the implications of SLC39A10 deficiency in various biological contexts, including cancer biology, developmental biology, and metabolic disorders. The precise modulation of zinc transport can shed light on its involvement in cellular processes such as apoptosis, proliferation, and differentiation, thereby advancing the understanding of complex disease mechanisms.

The scientific importance of SLC39A10 Gene Knockout Cell Lines lies in their application in both basic research and clinical investigations. These models offer a valuable tool for elucidating the pathophysiological roles of zinc and its transporters in disease states, providing opportunities for the development of targeted therapies. They can also facilitate the screening and evaluation of potential pharmacological agents that modulate zinc levels in cells.

Compared to traditional cell lines, SLC39A10 Gene Knockout Cell Lines offer unique advantages, including higher specificity in studying the functional consequences of zinc transport impairment. This specificity allows for more robust and reproducible results in experimental setups. Additionally, these knockout models can serve as essential controls in experiments that aim to elucidate the role of zinc in cellular physiology.

For researchers and clinicians seeking to advance their studies in the field of metal ion transport and its implications for human health, SLC39A10 Gene Knockout Cell Lines represent a groundbreaking resource. They provide an unprecedented opportunity to explore the nuances of zinc signaling and its effects on various biological processes.

Our company leverages extensive expertise in genetic engineering and cell biology, offering a wide range of innovative tools designed to facilitate cutting-edge research in biomedical sciences. With a commitment to quality and scientific integrity, we aim to support advancements that lead to significant discoveries in health and disease.

Please note that all services are for research use only. Not intended for any clinical use.

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