Gene: Slc38a2
Official Full Name: solute carrier family 38, member 2provided by RGD
Gene Summary: Enables amino acid transmembrane transporter activity. Involved in several processes, including amino acid import; cellular response to mechanical stimulus; and neutral amino acid transport. Located in several cellular components, including brush border; neuronal cell body; and sarcolemma. Biomarker of visual epilepsy. Orthologous to human SLC38A2 (solute carrier family 38 member 2). [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14007 | SLC38A2 Knockout cell line (HeLa) | Human | SLC38A2 | 1:3~1:6 | Negative | Online Inquiry |
KO14008 | SLC38A2 Knockout cell line (HCT 116) | Human | SLC38A2 | 1:2~1:4 | Negative | Online Inquiry |
KO14009 | SLC38A2 Knockout cell line (HEK293) | Human | SLC38A2 | 1:3~1:6 | Negative | Online Inquiry |
Slc38a2 Gene Knockout Cell Lines represent a highly specialized tool in biological research, specifically designed to investigate the function and regulation of the Slc38a2 gene, which encodes a sodium-coupled transporter involved in amino acid homeostasis. These cell lines are generated through advanced CRISPR-Cas9 gene-editing technology, ensuring precise knockout of the Slc38a2 gene, thus allowing researchers to explore the biological pathways influenced by this transporter and elucidate its role in cellular metabolism and signaling.
The primary function of Slc38a2 gene knockout cell lines lies in their ability to facilitate the study of amino acid transport mechanisms and their implications in health and disease. By removing the gene's expression, researchers can assess changes in transport activity, cellular response to nutrient availability, and alterations in mTOR signaling pathways, which are crucial for understanding metabolic disorders and stress responses. This knockout model is particularly valuable in examining the roles of amino acids in cancer biology, neurobiology, and various other physiological contexts.
The scientific importance of these cell lines extends beyond basic research, as they can also serve as powerful tools in the development of novel therapeutic strategies targeting amino acid transporters. Their application in drug discovery processes can provide insights into potential pharmacological interventions for diseases characterized by dysregulated nutrient metabolism.
What sets Slc38a2 Gene Knockout Cell Lines apart from alternative models is the specificity and efficiency of the knockout achieved, providing unparalleled accuracy in experimental outcomes. Moreover, they have been validated through rigorous testing, ensuring high reproducibility in data collection, which is paramount in research settings.
For researchers and clinicians, investing in Slc38a2 Gene Knockout Cell Lines means gaining access to a cutting-edge model that enhances the ability to investigate complex biological questions, leading to breakthroughs in understanding metabolic processes. Our company, with years of expertise in genetic engineering and cell line development, is committed to providing researchers with high-quality, reliable biological products that drive innovation and discovery in the life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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