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SLC37A3 Knockout Cell Lines

Gene: SLC37A3

Official Full Name: solute carrier family 37 member 3provided by HGNC

Gene Summary: Enables xenobiotic transmembrane transporter activity. Involved in xenobiotic transmembrane transport. Located in endoplasmic reticulum membrane and lysosomal membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO00324 SLC37A3 Knockout cell line (HeLa) Human SLC37A3 1:3~1:6 Negative Online Inquiry
KO25044 SLC37A3 Knockout cell line (HCT 116) Human SLC37A3 1:2~1:4 Negative Online Inquiry
KO25045 SLC37A3 Knockout cell line (HEK293) Human SLC37A3 1:3~1:6 Negative Online Inquiry
KO25046 SLC37A3 Knockout cell line (A549) Human SLC37A3 1:3~1:4 Negative Online Inquiry

Background

SLC37A3 Gene Knockout Cell Lines are specifically engineered cellular models that lack the SLC37A3 gene, which encodes a member of the solute carrier family responsible for facilitating glucose-6-phosphate transport across cellular membranes. By creating knockout variants, these cell lines allow researchers to investigate the role of SLC37A3 in glucose metabolism, insulin signaling, and cellular stress responses.

The primary functioning mechanism of SLC37A3-deficient cells revolves around altered metabolic pathways, offering insights into the gene's contribution to diseases such as diabetes and obesity. These cell lines enable scientists to dissect underlying biochemical processes in real-time, providing an invaluable tool for studying the effects of gene knockouts on cellular function and metabolism.

The scientific importance of SLC37A3 Gene Knockout Cell Lines extends to their applications in both basic research and clinical settings. Researchers can employ these models to explore therapeutic targets for metabolic disorders and to conduct drug efficacy studies, enhancing our understanding of how modifications in glucose handling can impact overall metabolic health.

What sets these cell lines apart from alternatives is their high fidelity in recapitulating physiological responses and their robustness in various experimental setups. This allows for reproducibility in research findings, empowering advancements in metabolic research and drug development.

For researchers and clinicians seeking to elucidate the complex mechanisms related to glucose metabolism and develop targeted therapies, SLC37A3 Gene Knockout Cell Lines represent a pivotal resource. They not only streamline the investigative process but also foster the discovery of innovative solutions to metabolic diseases. Our company, with its commitment to precision and quality in producing specialized biological tools, ensures that these cell lines are validated for reliability and performance, making them an essential addition to any research endeavor in metabolic science.

Please note that all services are for research use only. Not intended for any clinical use.

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