Gene: SLC31A1
Official Full Name: solute carrier family 31 member 1provided by HGNC
Gene Summary: The protein encoded by this gene is a high-affinity copper transporter found in the cell membrane. The encoded protein functions as a homotrimer to effect the uptake of dietary copper. [provided by RefSeq, Aug 2011]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO03712 | SLC31A1 Knockout cell line (HeLa) | Human | SLC31A1 | 1:3~1:6 | Negative | Online Inquiry |
KO03713 | SLC31A1 Knockout cell line (HCT 116) | Human | SLC31A1 | 1:2~1:4 | Negative | Online Inquiry |
KO03714 | SLC31A1 Knockout cell line (HEK293) | Human | SLC31A1 | 1:3~1:6 | Negative | Online Inquiry |
KO03715 | SLC31A1 Knockout cell line (A549) | Human | SLC31A1 | 1:3~1:4 | Negative | Online Inquiry |
SLC31A1 Gene Knockout Cell Lines are meticulously engineered cellular models designed to investigate the role of the SLC31A1 gene, which encodes a high-affinity copper transporter. These cell lines have been created using advanced CRISPR-Cas9 gene editing technology, resulting in precision deletions of the SLC31A1 gene across various cellular types. This knockout results in the disruption of copper ion homeostasis, allowing researchers to study the physiological and pathological consequences of copper dysregulation, including its implications in human diseases such as Wilson's disease and cancer.
One of the key functions of these cell lines is to facilitate the exploration of cellular responses to copper deficiency or overload. Researchers can assess changes in cellular metabolism, oxidative stress responses, and apoptosis pathways, yielding insights that are critical for both basic research and therapeutic development. Moreover, these cell lines can be employed to screen potential therapeutic agents or assess drug efficacy and toxicity in a copper-depleted environment, thereby supplying valuable data for pharmaceutical development.
The scientific importance of SLC31A1 Gene Knockout Cell Lines extends into various applications—ranging from fundamental research in biochemistry and molecular biology to translational studies in pharmacology and toxicology. Researchers can benefit from these models as they provide an innovative platform for investigating novel therapeutic strategies aimed at disorders related to copper metabolism.
What sets our SLC31A1 Gene Knockout Cell Lines apart from alternatives is the rigorous validation process that ensures specificity and reliability, paired with our commitment to providing comprehensive technical support and detailed characterizations of each cell line. Unlike generic cell models, our knockout lines offer targeted insights into the gene's role, significantly advancing research outcomes.
In conclusion, these cell lines represent a powerful tool for researchers and clinicians alike, enhancing their ability to unlock the complexities of copper transport and its related disorders. Leveraging extensive expertise in genetic modification and cell line development, our company is dedicated to empowering scientific discovery through innovative biological products, ensuring that our customers have access to top-tier resources essential for their research endeavors.
Please note that all services are for research use only. Not intended for any clinical use.
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