Gene: SLC2A6
Official Full Name: solute carrier family 2 member 6provided by HGNC
Gene Summary: Hexose transport into mammalian cells is catalyzed by a family of membrane proteins, including SLC2A6, that contain 12 transmembrane domains and a number of critical conserved residues.[supplied by OMIM, Jul 2002]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO00277 | SLC2A6 Knockout cell line (HeLa) | Human | SLC2A6 | 1:3~1:6 | Negative | Online Inquiry |
KO31113 | SLC2A6 Knockout cell line (HCT 116) | Human | SLC2A6 | 1:2~1:4 | Negative | Online Inquiry |
KO31114 | SLC2A6 Knockout cell line (HEK293) | Human | SLC2A6 | 1:3~1:6 | Negative | Online Inquiry |
KO31115 | SLC2A6 Knockout cell line (A549) | Human | SLC2A6 | 1:3~1:4 | Negative | Online Inquiry |
SLC2A6 Gene Knockout Cell Lines represent a significant innovation in cellular biology, designed to facilitate research into glucose transport mechanisms and related metabolic disorders. These knockout cell lines are engineered to lack the SLC2A6 gene, which encodes a glucose transporter that plays a critical role in cellular uptake of various sugars. By creating these specific mutations, researchers can isolate the effects of SLC2A6 deficiency on cellular metabolism, signaling pathways, and overall physiological functions.
The primary mechanism of these cell lines involves the disruption of normal glucose transport, allowing for meticulous observation of downstream effects that may occur in the absence of SLC2A6. This can provide insights into conditions such as diabetes, obesity, and certain cancers, where glucose metabolism is often disrupted. Key functions of SLC2A6, such as facilitating the transport of fructose and other hexoses, can lead to understanding how variations in sugar transport contribute to disease states.
The scientific importance of these cell lines is underscored by their broad applications in both research and clinical investigations. They serve as invaluable tools for studying metabolic pathways and testing therapeutic interventions aimed at correcting dysfunctions associated with glucose transport. This capability makes them essential for both academic laboratories and pharmaceutical companies focused on drug discovery.
Compared to alternative research tools, SLC2A6 Gene Knockout Cell Lines offer unmatched specificity, as they allow for targeted studies on the unique role of SLC2A6 without the confounding effects present in wild-type models. This specificity enhances data reliability and helps accelerate discoveries in diabetes and metabolic research.
For researchers and clinicians striving to unravel the complexities of metabolic diseases, these knockout cell lines provide critical value. They enable scientists to decipher the mechanistic underpinnings of glucose transport deficiencies and offer a platform for developing effective treatment strategies.
Our company prides itself on being at the forefront of genetic engineering and cell line development. With a commitment to quality and innovation, we deliver high-caliber products that support the scientific community in advancing research and enhancing therapeutic applications.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.