Gene: SLC25A36
Official Full Name: solute carrier family 25 member 36provided by HGNC
Gene Summary: Enables pyrimidine nucleotide transmembrane transporter activity. Involved in mitochondrial genome maintenance; pyrimidine nucleotide transport; and regulation of mitochondrial membrane potential. Located in mitochondrion. Implicated in familial hyperinsulinemic hypoglycemia 8. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14065 | SLC25A36 Knockout cell line (HeLa) | Human | SLC25A36 | 1:3~1:6 | Negative | Online Inquiry |
KO14066 | SLC25A36 Knockout cell line (HCT 116) | Human | SLC25A36 | 1:2~1:4 | Negative | Online Inquiry |
KO14067 | SLC25A36 Knockout cell line (HEK293) | Human | SLC25A36 | 1:3~1:6 | Negative | Online Inquiry |
KO14068 | SLC25A36 Knockout cell line (A549) | Human | SLC25A36 | 1:3~1:4 | Negative | Online Inquiry |
SLC25A36 Gene Knockout Cell Lines are specialized cellular models engineered to lack the SLC25A36 gene, known for its role in mitochondrial transport systems. These knockout models are invaluable tools for investigating the physiological and biochemical functions associated with mitochondrial activity and metabolism. The deletion of the SLC25A36 gene alters the transport dynamics of key metabolites across mitochondrial membranes, thereby enabling researchers to dissect pathways involved in cellular energy metabolism and disease states related to mitochondrial dysfunction.
The primary functionality of SLC25A36 knockout cell lines relies on the absence of this specific gene, which has been implicated in various mitochondrial processes, including the regulation of metabolic intermediates. This disruption facilitates the study of mitochondrial diseases, metabolic syndromes, and the effects of altered mitochondrial function on cellular signaling pathways. Researchers utilizing these cell lines can elucidate the underlying mechanisms of disease, assess drug responses, and even explore potential therapeutic targets.
From a scientific perspective, these knockout cell lines hold significant importance in both basic and applied research settings. They provide an accessible model for high-throughput screening of compounds that may mitigate mitochondrial dysfunction, thus holding promise for therapeutic developments. Compared to alternative cell lines that may have intact SLC25A36 function, these models offer a clearer understanding of the gene's role, allowing for more targeted research approaches.
The unique selling point of SLC25A36 Gene Knockout Cell Lines lies in their specificity and reliability, tailored for researchers focused on mitochondrial biology. They present a significant advantage in clarity of results, as researchers can confidently attribute phenotypic changes directly to the knockout of the gene of interest. Additionally, these cell lines are consistently validated for genetic integrity, ensuring the results generated are reproducible and relevant.
For researchers and clinicians involved in mitochondrial research or related fields, SLC25A36 Gene Knockout Cell Lines represent an essential asset to accelerate discoveries and foster innovative treatments for metabolic disorders. Our company leads in producing high-quality genetic models and vectors, underscoring our commitment to supporting scientific advancement and improving therapeutic outcomes.
Please note that all services are for research use only. Not intended for any clinical use.
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