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SLC25A22 Knockout Cell Lines

Gene: SLC25A22

Official Full Name: solute carrier family 25 member 22provided by HGNC

Gene Summary: This gene encodes a mitochondrial glutamate carrier. Mutations in this gene are associated with early infantile epileptic encephalopathy. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Jul 2010]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14069 SLC25A22 Knockout cell line (HeLa) Human SLC25A22 1:3~1:6 Negative Online Inquiry
KO14070 SLC25A22 Knockout cell line (HCT 116) Human SLC25A22 1:2~1:4 Negative Online Inquiry
KO14071 SLC25A22 Knockout cell line (HEK293) Human SLC25A22 1:3~1:6 Negative Online Inquiry
KO14072 SLC25A22 Knockout cell line (A549) Human SLC25A22 1:3~1:4 Negative Online Inquiry

Background

SLC25A22 Gene Knockout Cell Lines are genetically engineered cell lines that have been specifically modified to disrupt the SLC25A22 gene, which encodes for a mitochondrial carrier protein critical for the transport of various metabolites. By precisely knocking out this gene, researchers can study its role in cellular metabolism, mitochondrial function, and associated pathophysiological conditions. These cell lines serve as invaluable tools for elucidating the mechanisms underlying mitochondrial disorders and metabolic diseases where SLC25A22 has been implicated.

The key functions of the SLC25A22 protein involve the transport of glutamate and aspartate across the mitochondrial membrane, which is essential for maintaining cellular energy balance and metabolic homeostasis. By utilizing these knockout cell lines, researchers can observe the impact of the absence of this protein on mitochondrial energy production, cellular stress responses, and reactive oxygen species generation. This information is crucial for understanding the biological processes that contribute to diseases such as epilepsy and metabolic syndromes.

The scientific importance of SLC25A22 Gene Knockout Cell Lines extends beyond basic research; they are also poised for clinical applications, particularly in studies focused on drug development, genetic therapies, and metabolic engineering. Understanding the role of SLC25A22 in disease pathways can aid in creating targeted interventions and personalized medicine approaches.

What sets our SLC25A22 Gene Knockout Cell Lines apart from other genetic models is the precision of the knockout process and the functional validation performed. These lines are produced with rigorous quality control measures and are characterized to ensure consistent performance in experimental settings. This uniqueness grants users the confidence that they are working with a reliable model that accurately reflects physiological conditions.

For researchers and clinicians alike, the value of utilizing SLC25A22 Gene Knockout Cell Lines lies in their potential to drive significant discoveries in mitochondrial research and therapeutic development. They provide a sophisticated experimental platform that enhances our understanding of complex biological mechanisms, leading to more effective strategies for tackling metabolic diseases.

At [Your Company], we are committed to advancing biological research through high-quality products and innovative solutions. Our expertise in genetic engineering and dedication to scientific excellence ensure that our customers receive not only top-tier products but also the support necessary to foster groundbreaking research.

Please note that all services are for research use only. Not intended for any clinical use.

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