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SLC25A10 Knockout Cell Lines

Gene: SLC25A10

Official Full Name: solute carrier family 25 member 10provided by HGNC

Gene Summary: This gene encodes a member of a family of proteins that translocate small metabolites across the mitochondrial membrane. The encoded protein exchanges dicarboxylates, such as malate and succinate, for phosphate, sulfate, and other small molecules, thereby providing substrates for metabolic processes including the Krebs cycle and fatty acid synthesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO38387 SLC25A10 Knockout cell line (HeLa) Human SLC25A10 1:3~1:6 Negative Online Inquiry
KO38388 SLC25A10 Knockout cell line (HCT 116) Human SLC25A10 1:2~1:4 Negative Online Inquiry
KO38389 SLC25A10 Knockout cell line (HEK293) Human SLC25A10 1:3~1:6 Negative Online Inquiry
KO38390 SLC25A10 Knockout cell line (A549) Human SLC25A10 1:3~1:4 Negative Online Inquiry

Background

SLC25A10 Gene Knockout Cell Lines are genetically engineered cellular models that specifically lack the SLC25A10 gene, which encodes for a mitochondrial transporter involved in the transport of dicarboxylates across the mitochondrial membrane. By creating knockout versions of these cell lines, researchers can investigate the distinct physiological roles of the SLC25A10 protein and the metabolic pathways it influences.

Key functions of SLC25A10 include the regulation of mitochondrial metabolism and the facilitation of the metabolic exchange of intermediates between the mitochondria and cytoplasm, especially in processes such as gluconeogenesis and fatty acid metabolism. The mechanisms by which SLC25A10 exerts its functions are linked to cellular energy production and redox balance, making it a critical component in understanding energy homeostasis and metabolic disorders.

The scientific importance of SLC25A10 Knockout Cell Lines is pronounced in both research and clinical settings. These cell lines serve as vital tools for elucidating the precise biological roles of SLC25A10, aiding in the discovery of potential therapeutic targets for metabolic diseases and mitochondrial dysfunction. Furthermore, they can be employed to study the impact of SLC25A10 deficiency on cellular metabolism, which may provide insights into conditions such as diabetes, obesity, and certain cancers.

Compared to alternatives, the unique selling points of SLC25A10 Gene Knockout Cell Lines lie in their specificity and the precision with which they generate insights into metabolic pathways. Unlike other models, these knockout lines offer an unparalleled opportunity to explore the functional consequences of the loss of SLC25A10, facilitating the identification of compensatory mechanisms and the development of targeted interventions.

Researchers and clinicians will find value in these cell lines due to their ability to promote advanced studies in cellular metabolism, accurate modeling of human disease, and the opportunity to translate findings into potential diagnostic and therapeutic strategies. With a commitment to advancing scientific understanding, our company offers comprehensive resources, including technical support and product validation, ensuring that users maximize the potential of our SLC25A10 Gene Knockout Cell Lines in their groundbreaking research.

Please note that all services are for research use only. Not intended for any clinical use.

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