Gene: SHC3
Official Full Name: SHC adaptor protein 3provided by HGNC
Gene Summary: Enables phosphotyrosine residue binding activity. Predicted to be involved in cell surface receptor protein tyrosine kinase signaling pathway. Predicted to act upstream of or within glutamatergic synaptic transmission and learning or memory. Predicted to be located in cytosol. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO09035 | SHC3 Knockout cell line (HeLa) | Human | SHC3 | 1:3~1:6 | Negative | Online Inquiry |
SHC3 Gene Knockout Cell Lines are sophisticated cellular models that have been genetically engineered to disrupt the expression of the SHC3 gene, an essential component involved in various signaling pathways critical for cellular processes such as proliferation, differentiation, and stress response. By leveraging CRISPR-Cas9 technology, these cell lines enable researchers to study gene function and elucidate the role of SHC3 in pathophysiological contexts, particularly in cancer and neurodevelopmental disorders.
The key mechanism by which these knockout cell lines operate is through targeted genome editing, resulting in a complete loss of SHC3 expression. This loss permits the investigation of the consequent phenotypic and molecular changes, providing invaluable insights into signaling networks and their influence on cellular behavior. Consequently, SHC3 Gene Knockout Cell Lines are an indispensable tool for researchers aiming to explore gene function, screen drug targets, or develop targeted therapies.
In terms of scientific importance, these cell lines are critical in both research and clinical applications, notably facilitating the discovery of biomarkers and therapeutic targets that can lead to innovative treatment strategies. Their availability supports advancements in precision medicine, where understanding the specific role of genes can guide personalized healthcare solutions.
The advantages of SHC3 Gene Knockout Cell Lines include their ability to provide reproducible and reliable results that cannot be easily obtained using traditional model systems. Compared to other genetic perturbation methods like RNA interference, knockout models offer a more definitive approach to gene function analysis, ensuring clearer interpretations of experimental outcomes.
For researchers and clinicians, the value of SHC3 Gene Knockout Cell Lines lies in their potential to accelerate discoveries and enhance experimental rigor, ultimately contributing to breakthroughs in biomedical research. Backed by our company’s extensive expertise in genetic engineering and cell line development, our offerings promise high-quality, validated cell lines that empower the scientific community to push the boundaries of knowledge in genetics and therapeutics.
Please note that all services are for research use only. Not intended for any clinical use.
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