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SH3YL1 Knockout Cell Lines

Gene: SH3YL1

Official Full Name: SH3 and SYLF domain containing 1provided by HGNC

Gene Summary: Enables phosphatase binding activity and phosphatidylinositol binding activity. Predicted to be involved in regulation of ruffle assembly. Predicted to act upstream of or within phosphatidylinositol biosynthetic process. Located in ruffle membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO27991 SH3YL1 Knockout cell line (HeLa) Human SH3YL1 1:3~1:6 Negative Online Inquiry
KO27992 SH3YL1 Knockout cell line (HCT 116) Human SH3YL1 1:2~1:4 Negative Online Inquiry
KO27993 SH3YL1 Knockout cell line (HEK293) Human SH3YL1 1:3~1:6 Negative Online Inquiry
KO27994 SH3YL1 Knockout cell line (A549) Human SH3YL1 1:3~1:4 Negative Online Inquiry

Background

SH3YL1 Gene Knockout Cell Lines are genetically modified cell lines that have undergone targeted deletion of the SH3YL1 gene, which is implicated in various cellular processes including signaling pathways, cytoskeletal organization, and immune response modulation. This product serves as an indispensable tool for researchers aiming to elucidate the gene's biological roles and its contribution to various pathophysiological conditions, including cancer and autoimmune disorders.

The key function of these knockout cell lines lies in their ability to facilitate the study of gene function by allowing researchers to observe changes in cell behavior, signaling cascades, and phenotypic traits in the absence of the SH3YL1 gene. The mechanism behind their utility involves the analysis of loss-of-function phenotypes, providing insights into cellular mechanisms and potential therapeutic targets. By utilizing CRISPR-Cas9 or other gene-editing techniques to create these knockout lines, scientists can achieve precise modification, ensuring the elimination of undesired gene effects or compensatory mechanisms.

The scientific importance of SH3YL1 Gene Knockout Cell Lines is underscored by their applications in both bench research and clinical settings. In the lab, these cell lines enable high-throughput drug screening, identification of new therapeutic targets, and the study of disease mechanisms at a cellular level. Clinically, they can pave the way for advancements in personalized medicine by allowing for the development of targeted interventions based on the molecular understanding of SH3YL1's role.

Compared to alternative methodologies, such as transient knockdowns or chemical inhibitors, the permanence and specificity of knockout cell lines provide a more robust and consistent model for studying gene function and interaction networks. This ensures that researchers obtain reliable data across multiple experimental replications.

For researchers and clinicians, the SH3YL1 Gene Knockout Cell Lines represent a valuable addition to the toolkit for studying gene function and disease mechanisms, enabling deeper insights that drive innovation in therapeutic development. Our company prides itself on delivering high-quality, validated biological products, and our expertise in genetic engineering ensures that each cell line meets rigorous standards for reliability and performance.

Please note that all services are for research use only. Not intended for any clinical use.

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