Gene: SERPINA2
Official Full Name: serpin family A member 2 (gene/pseudogene)provided by HGNC
Gene Summary: This gene encodes a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. The encoded intracellular glycoprotein is localized at the endoplasmic reticulum. This gene is a polymorphic pseudogene, with the non-functional allele being predominant in some populations. Some individuals, as represented by the reference genome allele, contain a 2kb coding region deletion and a start code mutation. [provided by RefSeq, Feb 2014]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO20504 | SERPINA2 Knockout cell line (HeLa) | Human | SERPINA2 | 1:3~1:6 | Negative | Online Inquiry |
KO20505 | SERPINA2 Knockout cell line (HCT 116) | Human | SERPINA2 | 1:2~1:4 | Negative | Online Inquiry |
KO20506 | SERPINA2 Knockout cell line (HEK293) | Human | SERPINA2 | 1:3~1:6 | Negative | Online Inquiry |
KO20507 | SERPINA2 Knockout cell line (A549) | Human | SERPINA2 | 1:3~1:4 | Negative | Online Inquiry |
SERPINA2 Gene Knockout Cell Lines are engineered cell lines specifically designed to lack the SERPINA2 gene, which encodes the serpin A2 protein, a serine protease inhibitor implicated in several physiological processes, including immune response and cell growth regulation. These knockout models provide a powerful tool for studying the functional role of SERPINA2 in cellular mechanisms, allowing researchers to dissect pathways affected by the absence of this crucial protein.
The principal function of the SERPINA2 gene knockout is to facilitate the study of proteolytic pathways and their regulation. By eliminating the SERPINA2 gene, researchers can observe changes in cell behavior, protein interactions, and signaling pathways, providing insight into the biological roles of SERPINA2 in various disease models, including cancer and inflammatory responses. This gene knockout not only allows for in-depth mechanistic studies but also aids in pathway elucidation and drug target discovery.
The scientific importance of SERPINA2 Gene Knockout Cell Lines is evident in both research and clinical contexts, serving as a model for investigating diseases associated with altered serpin function. These models can significantly accelerate drug development and therapeutic strategies by providing a more accurate representation of disease mechanisms in vitro.
Compared to traditional cell lines that express SERPINA2, our knockout cell lines offer the unique advantage of enabling researchers to understand the specific contributions of SERPINA2 to cellular functions. This capability is crucial for targeting specific pathways without confounding effects due to the presence of the protein, thus increasing the reliability of experimental results.
For researchers and clinicians focused on mechanistic cell biology, drug development, or translational medicine, SERPINA2 Gene Knockout Cell Lines provide an invaluable resource. They enable a more focused approach to understanding SERPINA2's role in health and disease, driving advancements in personalized medicine and innovative therapeutics.
Our company leverages years of expertise in genetic engineering and cellular biology to offer high-quality biological products, including these knockout cell lines, supporting your cutting-edge research with robust tools that enhance scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.