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SERGEF Knockout Cell Lines

Gene: SERGEF

Official Full Name: secretion regulating guanine nucleotide exchange factorprovided by HGNC

Gene Summary: Predicted to enable guanyl-nucleotide exchange factor activity. Involved in negative regulation of protein secretion. Located in cytosol and nucleoplasm. Biomarker of atherosclerosis. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28126 SERGEF Knockout cell line (HeLa) Human SERGEF 1:3~1:6 Negative Online Inquiry
KO28127 SERGEF Knockout cell line (HCT 116) Human SERGEF 1:2~1:4 Negative Online Inquiry
KO28128 SERGEF Knockout cell line (HEK293) Human SERGEF 1:3~1:6 Negative Online Inquiry
KO28129 SERGEF Knockout cell line (A549) Human SERGEF 1:3~1:4 Negative Online Inquiry

Background

SERGEF Gene Knockout Cell Lines are advanced biological tools that facilitate the study of gene function by enabling precise gene disruption in various cell types. These cell lines are developed using cutting-edge CRISPR/Cas9 gene-editing technology, allowing for the targeted knockout of specific genes, which is crucial for elucidating gene pathways and understanding various biological processes. The key mechanism involves the introduction of guide RNA sequences that direct the Cas9 nuclease to the desired genomic locus, leading to double-strand breaks and subsequent gene inactivation through cellular repair processes.

The scientific importance of SERGEF Gene Knockout Cell Lines lies in their broad applicability across multiple research fields, including cancer biology, neurobiology, and metabolic disorders. Researchers can use these cell lines to investigate the role of specific genes in disease pathogenesis, drug response, and cellular signaling pathways, thereby advancing knowledge and contributing to the development of novel therapeutic strategies.

What sets SERGEF Gene Knockout Cell Lines apart from other alternatives is their high targeting efficiency, low off-target effects, and the variety of cell types offered, including commonly used models such as HEK293, HeLa, and more specialized lines. This versatility ensures that researchers can find the optimal model for their studies, saving time and resources while yielding reproducible results.

For researchers and clinicians, the value of SERGEF Gene Knockout Cell Lines lies in their ability to generate reliable and efficient gene disruptions, providing enhanced insights into gene function and its implications in health and disease. By leveraging these tools, users can significantly contribute to advancing scientific knowledge and developing targeted therapies.

Our company has established itself as a leader in the biotechnology field by focusing on innovation and quality. We leverage our expertise in cell line development and gene editing to provide researchers with reliable tools that aid in transformative discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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