Gene: SEMA4F
Official Full Name: ssemaphorin 4Fprovided by HGNC
Gene Summary: This gene encodes a transmembrane class IV semaphorin family protein, which plays a role in neural development. This gene may be involved in neurogenesis in prostate cancer, the development of neurofibromas, and breast cancer tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO31783 | SEMA4F Knockout cell line (HeLa) | Human | SEMA4F | 1:3~1:6 | Negative | Online Inquiry |
KO31784 | SEMA4F Knockout cell line (HCT 116) | Human | SEMA4F | 1:2~1:4 | Negative | Online Inquiry |
KO31785 | SEMA4F Knockout cell line (HEK293) | Human | SEMA4F | 1:3~1:6 | Negative | Online Inquiry |
KO31786 | SEMA4F Knockout cell line (A549) | Human | SEMA4F | 1:3~1:4 | Negative | Online Inquiry |
SEMA4F Gene Knockout Cell Lines are state-of-the-art biological tools designed to enable researchers to investigate the functional roles of the SEMA4F gene in various cellular contexts. This gene encodes for a member of the semaphorin family, known for its critical involvement in cell signaling, neuronal development, and immune regulation. Knockout of this gene allows for the detailed study of its contributions to cell migration, axon guidance, and intercellular communication.
The key function of SEMA4F Gene Knockout Cell Lines lies in their ability to lack the expression of the SEMA4F protein, providing a unique platform to elucidate the gene's role in signaling pathways that govern cellular behavior. By utilizing CRISPR-Cas9 technology, these cell lines ensure precise gene disruption, offering investigators a reliable model system to explore the implications of SEMA4F knockout on key biological processes, such as tumorigenesis and immune responses.
The scientific importance of these cell lines extends to various research and clinical applications. They are particularly valuable in immunology and cancer research, where understanding the SEMA4F pathway may inform therapeutic strategies targeting tumor-immune interactions. By elucidating the role of SEMA4F in these contexts, researchers can advance our understanding of disease mechanisms and contribute to the development of innovative treatment modalities.
Compared to alternative models, SEMA4F Gene Knockout Cell Lines are characterized by their high specificity and resilience, which enhances reproducibility in experimental settings. Moreover, as pre-validated and ready-to-use models, they save researchers time and resources by eliminating the need for extensive gene editing procedures.
This product's value to researchers and clinicians lies in its potential to unlock new avenues for exploration within the fields of developmental biology, neurobiology, and oncogenesis. By providing a tool to dissect the multifaceted roles of SEMA4F, researchers can contribute to foundational knowledge that drives future discoveries and clinical applications.
Our company is dedicated to advancing research capabilities through innovative biological products. With a focus on quality and reliability, we offer a comprehensive portfolio that supports scientists in their quest to understand complex biological systems.
Please note that all services are for research use only. Not intended for any clinical use.
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