Gene: SEMA3D
Official Full Name: semaphorin 3Dprovided by HGNC
Gene Summary: This gene encodes a member of the semaphorin III family of secreted signaling proteins that are involved in axon guidance during neuronal development. The encoded protein contains an N-terminal Sema domain, an immunoglobulin like domain and a C-terminal basic domain. The protein encoded by this gene binds neuropilin and plays an important role in cardiovascular development. [provided by RefSeq, Aug 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26801 | SEMA3D Knockout cell line (HeLa) | Human | SEMA3D | 1:3~1:6 | Negative | Online Inquiry |
KO26802 | SEMA3D Knockout cell line (HCT 116) | Human | SEMA3D | 1:2~1:4 | Negative | Online Inquiry |
KO26803 | SEMA3D Knockout cell line (HEK293) | Human | SEMA3D | 1:3~1:6 | Negative | Online Inquiry |
SEMA3D Gene Knockout Cell Lines are precision-engineered cellular models designed to study the function and role of the SEMA3D gene in various biological processes. Utilizing CRISPR-Cas9 gene editing technology, these cell lines enable the complete ablation of the SEMA3D gene, which encodes a member of the semaphorin family implicated in axonal guidance, immune response modulation, and tumor progression. By providing a method to investigate gene function with high specificity, SEMA3D Gene Knockout Cell Lines facilitate a deeper understanding of the molecular pathways influenced by SEMA3D.
The primary mechanism of action involves the targeted disruption of the SEMA3D gene, leading to an array of physiological changes that can be extensively characterized. Researchers can employ these knockout models to explore the gene’s contributions to cell signaling, cell migration, and interaction with the extracellular matrix, making it a valuable tool for studying neurodevelopmental disorders, cancer biology, and autoimmune conditions.
From a scientific perspective, SEMA3D Gene Knockout Cell Lines hold immense potential in both basic research and therapeutic development. Their applications extend to drug testing and biomarker discovery, enabling researchers to elucidate the functional relevance of SEMA3D in various disease contexts.
What sets these cell lines apart from traditional models is their high specificity and reliability, reducing background noise in experimental results. Compared to other gene editing approaches, the CRISPR technology used ensures precise alterations with limited off-target effects, enhancing the integrity of research findings.
For researchers and clinicians, the availability of SEMA3D Gene Knockout Cell Lines offers an invaluable resource to bridge the gap between basic science and clinical application, promoting innovative therapeutic strategies. Our company specializes in developing advanced biological products, ensuring that our offerings – including the SEMA3D Gene Knockout Cell Lines – are backed by rigorous quality control and scientific expertise, making us a trusted partner in the realm of molecular research.
Please note that all services are for research use only. Not intended for any clinical use.
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