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SEMA3B Knockout Cell Lines

Gene: SEMA3B

Official Full Name: semaphorin 3Bprovided by HGNC

Gene Summary: The protein encoded by this gene belongs to the class-3 semaphorin/collapsin family, whose members function in growth cone guidance during neuronal development. This family member inhibits axonal extension and has been shown to act as a tumor suppressor by inducing apoptosis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO34409 SEMA3B Knockout cell line (HeLa) Human SEMA3B 1:3~1:6 Negative Online Inquiry
KO34410 SEMA3B Knockout cell line (HCT 116) Human SEMA3B 1:2~1:4 Negative Online Inquiry
KO34411 SEMA3B Knockout cell line (HEK293) Human SEMA3B 1:3~1:6 Negative Online Inquiry
KO34412 SEMA3B Knockout cell line (A549) Human SEMA3B 1:3~1:4 Negative Online Inquiry

Background

SEMA3B Gene Knockout Cell Lines are meticulously engineered cellular systems designed to facilitate the study of the SEMA3B gene's role in cellular processes such as neurogenesis, axon guidance, and immune response modulation. By utilizing CRISPR-Cas9 gene editing technology, these knockout cell lines provide researchers with a powerful tool to investigate the specific biological functions of SEMA3B, a member of the semaphorin family known for its involvement in regulating cell signaling pathways and cellular interactions.

The SEMA3B gene produces a secreted protein that acts as a repellent in the context of neural development and can influence tumor microenvironment dynamics. By knocking out SEMA3B in these cell lines, researchers can examine downstream signaling pathways affected by the absence of this protein. This allows for a greater understanding of the intricate mechanisms of cell communication and how dysregulation can lead to various diseases, including cancer.

In both research and clinical settings, the applications of SEMA3B Gene Knockout Cell Lines are profound. They facilitate the investigation of potential therapeutic targets in oncology, as changes in SEMA3B expression have been linked to cancer progression. Additionally, they are instrumental in neurobiology research to elucidate the intricate roles of semaphorins in neuronal development and connectivity.

What sets our SEMA3B Gene Knockout Cell Lines apart from other genetic models is their precision, validated performance, and ease of use. Unlike traditional gene knockouts that may involve extensive laborious processes, our cell lines provide ready-to-use models that yield reproducible results, saving time and resources for labs. Furthermore, data generated from these knockout models can be directly compared across studies, amplifying the impact of findings in the field.

In short, SEMA3B Gene Knockout Cell Lines are invaluable tools for researchers and clinicians alike, enabling groundbreaking studies that unlock new insights into cellular behavior and disease mechanisms. At our company, we are dedicated to providing high-quality, precision genetic products tailored for advancements in biological research, supported by expertise that ensures our clients have access to the best resources available.

Please note that all services are for research use only. Not intended for any clinical use.

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