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SEC14L4 Knockout Cell Lines

Gene: SEC14L4

Official Full Name: SEC14 like lipid binding 4provided by HGNC

Gene Summary: The protein encoded by this gene is highly similar to the protein encoded by the Saccharomyces cerevisiae SEC14 gene. The SEC14 protein is a phophatidylinositol transfer protein that is essential for biogenesis of Golgi-derived transport vesicles, and thus is required for the export of yeast secretory proteins from the Golgi complex. The specific function of this protein has not yet been determined. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2009]

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Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14249 SEC14L4 Knockout cell line (HCT 116) Human SEC14L4 1:2~1:4 Negative Online Inquiry
KO14250 SEC14L4 Knockout cell line (A549) Human SEC14L4 1:3~1:4 Negative Online Inquiry

Background

SEC14L4 Gene Knockout Cell Lines represent a critical tool for researchers seeking to investigate the functional roles of the SEC14L4 gene and its implications in cellular processes. The SEC14L4 gene encodes a protein that is believed to play a significant role in lipid metabolism and membrane trafficking. By providing knockout (KO) cell lines that lack this specific gene, researchers can explore the gene’s contribution to various biological pathways and disease mechanisms more effectively.

The key function of these cell lines lies in their ability to facilitate the study of SEC14L4-related pathways without the interference of its protein products. This is achieved through CRISPR/Cas9 gene editing technology, which ensures high specificity and efficiency in disrupting the target gene. Such cellular models are essential in elucidating the downstream effects of gene loss, including changes in lipid composition, signaling cascades, and potential impacts on cell growth and proliferation.

The scientific importance of SEC14L4 Gene Knockout Cell Lines extends to both academic research and clinical applications. They can be utilized in pharmacological studies aimed at identifying potential therapeutic targets for metabolic disorders and certain cancers associated with lipid dysregulation. Moreover, they serve as valuable assets in the biotech industry for drug development, as understanding gene function in cellular contexts can lead to novel interventions.

Unlike alternative cell lines, the SEC14L4 Gene Knockout Cell Lines provide a novel and highly specific model that decreases variability and improves reproducibility in experiments. Their unique genetic makeup allows for a clearer interpretation of results, positioning them as a superior choice for researchers focused on lipid biology and related fields.

In summary, SEC14L4 Gene Knockout Cell Lines are indispensable for any laboratory engaged in cutting-edge research on gene functions and cellular metabolism. This product is a testament to our company's commitment to providing high-quality, precise biological products that empower the research community. Our team's expertise in genetic engineering ensures that each cell line is rigorously validated for optimal performance, making them an ideal choice for advancing scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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