Gene: SDSL
Official Full Name: serine dehydratase likeprovided by HGNC
Gene Summary: Enables L-serine ammonia-lyase activity; identical protein binding activity; and threonine deaminase activity. Predicted to be involved in L-serine catabolic process; isoleucine biosynthetic process; and threonine catabolic process. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO30818 | SDSL Knockout cell line (HeLa) | Human | SDSL | 1:3~1:6 | Negative | Online Inquiry |
KO30819 | SDSL Knockout cell line (HCT 116) | Human | SDSL | 1:2~1:4 | Negative | Online Inquiry |
KO30820 | SDSL Knockout cell line (HEK293) | Human | SDSL | 1:3~1:6 | Negative | Online Inquiry |
KO30821 | SDSL Knockout cell line (A549) | Human | SDSL | 1:3~1:4 | Negative | Online Inquiry |
SDSL Gene Knockout Cell Lines are advanced cellular models specifically engineered to facilitate the study of gene function and regulation through the targeted disruption of specific genes. Utilizing cutting-edge CRISPR-Cas9 technology, SDSL (Site-Directed Selective Locus) Gene Knockout Cell Lines enable researchers to create precise gene deletions, allowing for a deeper understanding of gene interactions and their roles in various biological processes.
The mechanism behind these knockout cell lines revolves around the ability of the CRISPR-Cas9 system to introduce double-strand breaks at predetermined genomic locations. This targeted approach allows for efficient gene disruption through non-homologous end joining (NHEJ), enabling scientists to investigate the phenotypic consequences of gene loss, which is essential in elucidating pathways involved in disease and therapeutic responses. These cell lines serve as invaluable tools in functional genomics, drug discovery, and the study of genetic diseases.
From a scientific standpoint, the SDSL Gene Knockout Cell Lines hold significant promise for both research and clinical applications. They can model diseases such as cancer, neurodegenerative disorders, and metabolic syndromes, ultimately paving the way for personalized medicine approaches. Furthermore, they offer a robust platform for high-throughput screening of drug candidates, expediting the drug development pipeline.
What sets SDSL Gene Knockout Cell Lines apart from traditional knockout models is their enhanced specificity and reduced off-target effects, providing researchers with greater confidence in their experimental outcomes. These cell lines are validated for consistency, reproducibility, and efficiency, making them a superior choice for scientists focused on precision and reliability in their research.
In conclusion, SDSL Gene Knockout Cell Lines represent a vital resource for researchers and clinicians aiming to advance their understanding of gene function in health and disease. By choosing our product, users align themselves with a company that prides itself on its expertise in biotechnological innovations and a commitment to providing reliable, state-of-the-art research tools that drive scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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