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SDC3 Knockout Cell Lines

Gene: SDC3

Official Full Name: syndecan 3provided by HGNC

Gene Summary: The protein encoded by this gene belongs to the syndecan proteoglycan family. It may play a role in the organization of cell shape by affecting the actin cytoskeleton, possibly by transferring signals from the cell surface in a sugar-dependent mechanism. Allelic variants of this gene have been associated with obesity. [provided by RefSeq, Oct 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO02833 SDC3 Knockout cell line (HeLa) Human SDC3 1:3~1:6 Negative Online Inquiry
KO02834 SDC3 Knockout cell line (HCT 116) Human SDC3 1:2~1:4 Negative Online Inquiry
KO02835 SDC3 Knockout cell line (HEK293) Human SDC3 1:3~1:6 Negative Online Inquiry
KO02836 SDC3 Knockout cell line (A549) Human SDC3 1:3~1:4 Negative Online Inquiry

Background

SDC3 Gene Knockout Cell Lines are genetically engineered cells specifically designed to lack the Syndecan-3 (SDC3) gene, which is crucial for various cellular processes, including cell adhesion, growth, and signaling. These cell lines are invaluable tools for researchers investigating the role of SDC3 in physiological and pathological contexts, particularly in cancer biology, cardiovascular research, and neurobiology. By elucidating how the absence of SDC3 affects cellular behavior and contributes to disease states, scientists can gain insights into potential therapeutic targets and pathways.

The key function of SDC3 gene knockout cells lies in their ability to provide a controlled environment in which the consequences of SDC3 deficiency are observed. Mechanistically, SDC3 is involved in modulating interactions between cells and the extracellular matrix, influencing processes such as migration, proliferation, and differentiation. By studying these knockout lines, researchers can dissect the molecular pathways affected by SDC3, enabling a deeper understanding of its role in tissue homeostasis and disease progression.

The scientific importance of SDC3 Gene Knockout Cell Lines extends to various applications in research and clinical settings, including drug development and biomarker identification. Given that SDC3 is implicated in several diseases, knockout models can facilitate the evaluation of novel therapeutics aimed at diseases associated with altered SDC3 expression.

Compared to alternative models, such as wild-type cells or transient knockdown systems, SDC3 gene knockout cell lines offer the advantage of stable, long-term gene deficiency. This stability ensures reproducibility and reliable data, critical factors in scientific research. Furthermore, these cell lines provide a platform for high-throughput screening, which can accelerate the pace of discovery in both basic and applied research.

For researchers and clinicians eager to explore the unexplored territories of SDC3's function in health and disease, these knockout cell lines represent a valuable resource. By enabling the examination of the gene's biological roles, the implications of its manipulation can translate into significant contributions toward therapeutic innovations.

Our company specializes in providing high-quality biological products tailored to the needs of the research community, leveraging expertise in genetic engineering and cell line development. With a commitment to advancing scientific discovery, we ensure our products are rigorously validated and supported by comprehensive technical resources.

Please note that all services are for research use only. Not intended for any clinical use.

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