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SCARF2 Knockout Cell Lines

Gene: SCARF2

Official Full Name: scavenger receptor class F member 2provided by HGNC

Gene Summary: The protein encoded by this gene is similar to SCARF1/SREC-I, a scavenger receptor protein that mediates the binding and degradation of acetylated low density lipoprotein (Ac-LDL). This protein has only little activity of internalizing modified low density lipoproteins (LDL), but it can interact with SCARF1 through its extracellular domain. The association of this protein with SCARF1 is suppressed by the presence of scavenger ligands. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO07186 SCARF2 Knockout cell line (HCT 116) Human SCARF2 1:2~1:4 Negative Online Inquiry
KO07187 SCARF2 Knockout cell line (HEK293) Human SCARF2 1:3~1:6 Negative Online Inquiry

Background

SCARF2 Gene Knockout Cell Lines represent an advanced biotechnological tool designed for the functional analysis of the SCARF2 (Scavenger Receptor Class F Member 2) gene. These engineered cell lines have been systematically developed using CRISPR-Cas9 technology, resulting in precise deletions or disruptions of the SCARF2 gene. The primary function of these knockout cell lines is to facilitate the investigation of SCARF2’s biological roles in cellular processes, particularly in immune responses and inflammation. By examining these specific knockout cell lines, researchers can delineate signaling pathways, investigate the metabolic consequences of SCARF2 loss, and elucidate its involvement in various diseases, including cardiovascular and neurodegenerative disorders.

The scientific importance of SCARF2 Gene Knockout Cell Lines is underscored by their wide-ranging applications in both basic and translational research. These cell lines serve as invaluable models for studying immunological mechanisms and developing therapeutic targets, offering insights that can lead to innovative treatment strategies for diseases linked to SCARF2 dysregulation. Furthermore, their accessibility for genetic manipulation makes them an ideal choice for laboratories focused on gene function characterization and drug screening.

Key advantages of the SCARF2 Gene Knockout Cell Lines include their high specificity, reproducibility, and the ability to use them in various experimental setups, including high-throughput screening and co-culture systems. This specificity reduces off-target effects commonly seen with less advanced methods, providing clarity in experimental outcomes. These unique selling points ensure that researchers have reliable and precise models that can enhance the quality of scientific data generated.

For clinicians and researchers aiming to unravel the complexities of SCARF2 functions and its impact on health, SCARF2 Gene Knockout Cell Lines offer a powerful solution that bridges fundamental research and clinical applications. The ability to study this gene in a controlled environment accelerates discovery and innovation in developing potential therapies.

Our company is at the forefront of biological product development, leveraging cutting-edge techniques and extensive expertise in genetics and cell biology to offer high-quality cell lines tailored to meet the evolving needs of the research community. We pride ourselves on providing researchers with the tools necessary for groundbreaking discoveries.

Please note that all services are for research use only. Not intended for any clinical use.

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