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SCAMP5 Knockout Cell Lines

Gene: SCAMP5

Official Full Name: secretory carrier membrane protein 5provided by HGNC

Gene Summary: Involved in positive regulation of cytokine production; regulation of vesicle-mediated transport; and response to endoplasmic reticulum stress. Located in Golgi apparatus; plasma membrane; and recycling endosome membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14327 SCAMP5 Knockout cell line (HeLa) Human SCAMP5 1:3~1:6 Negative Online Inquiry
KO14328 SCAMP5 Knockout cell line (HCT 116) Human SCAMP5 1:2~1:4 Negative Online Inquiry
KO14329 SCAMP5 Knockout cell line (HEK293) Human SCAMP5 1:3~1:6 Negative Online Inquiry
KO14330 SCAMP5 Knockout cell line (A549) Human SCAMP5 1:3~1:4 Negative Online Inquiry

Background

SCAMP5 Gene Knockout Cell Lines represent a groundbreaking evolution in the study of cellular mechanisms underlying neurotransmitter release and synaptic function. SCAMP5 (Secretory Carrier Membrane Protein 5) plays a critical role in the regulation of vesicle trafficking and exocytosis, essential processes for neurotransmission and cellular communication. These specially developed knockout cell lines permit researchers to investigate the consequences of SCAMP5 deficiency, providing insights into its physiological roles and potential implications in neurodevelopmental disorders.

The key function of SCAMP5 Gene Knockout Cell Lines lies in their ability to model the functional consequences of SCAMP5 loss. By disrupting the SCAMP5 gene, these cell lines allow for the examination of related cellular pathways, such as synaptic plasticity and calcium signaling, that are pivotal in neuroscience research. Researchers can utilize these cell lines to explore various aspects of neuron behavior, including vesicle release patterns, receptor functionality, and synaptic integrity.

The scientific importance of this product extends to both fundamental research and clinical applications. Understanding SCAMP5’s role could unveil novel therapeutic targets for conditions such as autism spectrum disorders and schizophrenia, where synaptic dysfunction plays a significant role. Moreover, these knockout lines offer a valuable tool for drug discovery efforts aimed at modulating synaptic activity.

What sets SCAMP5 Gene Knockout Cell Lines apart from alternative models is their specificity and adaptability. Unlike traditional genetic models, these cell lines retain the cellular environment and can be used in high-throughput systems for pharmacological screening. Their ease of manipulation and characterization increases their appeal to researchers seeking to maximize efficiency in their studies.

For researchers and clinicians dedicated to advancing neurobiological knowledge, SCAMP5 Gene Knockout Cell Lines are indispensable. This innovative tool empowers scientists to dissect complex synaptic dynamics, potentially leading to significant breakthroughs in understanding neurobehavioral health.

Our company has extensive expertise in developing cutting-edge biological research tools, ensuring that our products are tailored to meet the evolving demands of the scientific community. We are committed to providing high-quality research solutions, enabling innovations that may lead to transformative discoveries in cellular and molecular biology.

Please note that all services are for research use only. Not intended for any clinical use.

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