Gene: SAP25
Official Full Name: Sin3A associated protein 25provided by HGNC
Gene Summary: Predicted to be involved in negative regulation of DNA-templated transcription. Predicted to be located in cytoplasm. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14361 | SAP25 Knockout cell line (HeLa) | Human | SAP25 | 1:3~1:6 | Negative | Online Inquiry |
KO14362 | SAP25 Knockout cell line (HCT 116) | Human | SAP25 | 1:2~1:4 | Negative | Online Inquiry |
KO14363 | SAP25 Knockout cell line (HEK293) | Human | SAP25 | 1:3~1:6 | Negative | Online Inquiry |
SAP25 Gene Knockout Cell Lines represent a groundbreaking advancement in genetic research, offering scientists a powerful tool for the in-depth study of gene function, regulation, and the role of SAP25 in various biological processes. These cell lines have been engineered to lack the SAP25 gene, which encodes a protein vital in several cellular pathways, notably those involved in chromatin remodeling and transcriptional regulation. By providing a model system where the influence of SAP25 can be directly assessed, researchers can delve into its contributions to essential cellular functions and disease mechanisms.
The primary function of these knockout cell lines involves the elimination of the SAP25 protein, allowing for the examination of phenotypic outcomes that arise from the absence of this gene. Utilizing CRISPR-Cas9 technology, these cell lines ensure precise and efficient gene editing, minimizing off-target effects and enhancing reliability. The knockout model enables researchers to investigate the downstream effects on gene expression profiles, cellular proliferation, and response to pharmacological agents, facilitating a comprehensive analysis of gene function.
Scientifically, SAP25 Gene Knockout Cell Lines have significant applications in both fundamental research and clinical settings. They are instrumental in studies focused on cancer biology, as alterations in chromatin dynamics are frequently implicated in tumorigenesis. Furthermore, these cell lines can be utilized in drug development and testing, offering insights into the efficacy of novel therapeutic agents targeting related pathways.
What sets SAP25 Gene Knockout Cell Lines apart from alternative models is their user-friendly nature, availability of extensive validation data, and the assurance of reproducibility in experimental results. Researchers will find these cell lines beneficial for generating consistent and comparable data, ultimately expediting their discoveries.
The intrinsic value of SAP25 Gene Knockout Cell Lines lies in their capacity to deepen our understanding of gene-gene interactions and the complexities of cellular regulation, which can pave the way for innovative therapeutic strategies. With a commitment to high-quality biological products, our company stands at the forefront of genetic research solutions, fostering advancements that drive discovery and innovation in life sciences.
Please note that all services are for research use only. Not intended for any clinical use.
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