Gene: SAMD9
Official Full Name: sterile alpha motif domain containing 9provided by HGNC
Gene Summary: This gene encodes a sterile alpha motif domain-containing protein. The encoded protein localizes to the cytoplasm and may play a role in regulating cell proliferation and apoptosis. Mutations in this gene are the cause of normophosphatemic familial tumoral calcinosis. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, Jul 2010]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO05542 | SAMD9 Knockout cell line (HeLa) | Human | SAMD9 | 1:3~1:6 | Negative | Online Inquiry |
KO05543 | SAMD9 Knockout cell line (HCT 116) | Human | SAMD9 | 1:2~1:4 | Negative | Online Inquiry |
KO05544 | SAMD9 Knockout cell line (HEK293) | Human | SAMD9 | 1:3~1:6 | Negative | Online Inquiry |
KO05545 | SAMD9 Knockout cell line (A549) | Human | SAMD9 | 1:3~1:4 | Negative | Online Inquiry |
SAMD9 Gene Knockout Cell Lines are genetically altered mammalian cells in which the SAMD9 gene has been disrupted, providing a powerful tool for researchers investigating the biological roles of this gene and its implications in various cellular processes. The knockout of the SAMD9 gene allows for the in-depth study of its contributions to mechanisms such as cell signaling, apoptosis, and host-pathogen interactions. By eliminating the expression of SAMD9, these cell lines elucidate the gene's functional significance and its potential implications in diseases, particularly cancer and viral infections.
These cell lines operate by featuring a targeted disruption of the SAMD9 locus, typically achieved using CRISPR-Cas9 or other gene-editing technologies. As a result, they excel in studying the effects of SAMD9 deficiency on cellular behavior, allowing researchers to observe alterations in pathways such as immune response and cellular growth regulation. The versatility of these cell lines makes them suitable for a wealth of applications, ranging from basic research to drug development.
Scientific importance lies in their ability to model disease states more accurately, enabling the investigation of therapeutic strategies and the identification of potential drug targets. Unlike traditional methods, SAMD9 Gene Knockout Cell Lines provide a more refined approach to studying gene function in a controlled environment, facilitating high-throughput screening and personalized medicine discoveries.
The unique selling points of these cell lines include their precise gene modification, ease of use in experimental designs, and compatibility with various assays such as infection models and drug sensitivity screens. Compared to alternative methods which may rely on temporary gene knockdown, SAMD9 knockouts offer a stable and reproducible system for long-term studies.
For researchers and clinicians, the SAMD9 Gene Knockout Cell Lines present a valuable asset in unraveling the complexities of gene function and disease biology. They empower scientists to drive innovation in therapeutic development while enhancing our understanding of critical cellular mechanisms.
Our company, with its strong background in genetic engineering and cellular biology, is committed to providing high-quality biological products like the SAMD9 Gene Knockout Cell Lines, supporting the global research community in achieving their scientific goals.
Please note that all services are for research use only. Not intended for any clinical use.
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