Gene: SAC3D1
Official Full Name: SAC3 domain containing 1provided by HGNC
Gene Summary: Predicted to be involved in centrosome duplication and spindle assembly. Predicted to act upstream of or within negative regulation of receptor signaling pathway via JAK-STAT and regulation of immune response. Predicted to be located in microtubule cytoskeleton. Predicted to be part of protein-containing complex. Predicted to be active in centrosome; nucleus; and spindle. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO26971 | SAC3D1 Knockout cell line (HeLa) | Human | SAC3D1 | 1:3~1:6 | Negative | Online Inquiry |
KO26972 | SAC3D1 Knockout cell line (HCT 116) | Human | SAC3D1 | 1:2~1:4 | Negative | Online Inquiry |
KO26973 | SAC3D1 Knockout cell line (HEK293) | Human | SAC3D1 | 1:3~1:6 | Negative | Online Inquiry |
KO26974 | SAC3D1 Knockout cell line (A549) | Human | SAC3D1 | 1:3~1:4 | Negative | Online Inquiry |
SAC3D1 Gene Knockout Cell Lines are specially engineered cell lines that have undergone a targeted genetic modification to disrupt the SAC3D1 gene, which is implicated in various cellular processes, including RNA export and cytoplasmic mRNA localization. By knocking out this gene, researchers can create a cellular model that elucidates the functional roles of SAC3D1, offering insights into cellular mechanisms associated with gene expression and regulation.
The primary function of SAC3D1 Gene Knockout Cell Lines is to serve as a valuable tool for studying the consequences of SAC3D1 loss-of-function in both normal and pathological states. The mechanism underlying their utility lies in the ability to observe the resulting phenotypic changes in various cellular processes, such as RNA metabolism and protein synthesis pathways, allowing for the assessment of the gene's role in cellular homeostasis and disease progression.
Scientifically, these cell lines play a crucial role in advancing our understanding of genetic contributions to diseases, particularly in cancer and neurodegenerative disorders, where dysregulation of RNA transport is often noted. In clinical research, they offer a platform for testing therapeutic interventions that target SAC3D1-related pathways, fostering the development of novel strategies to modulate gene expression and cellular functions.
Compared to other gene knockout models, SAC3D1 Cell Lines have been rigorously validated for consistent performance and reproducibility, ensuring reliable experimental outcomes. Their specificity in targeting the SAC3D1 gene, along with well-characterized background strains, distinguishes them from traditional knockout models that may have off-target effects or variable expression profiles.
The value of SAC3D1 Gene Knockout Cell Lines to researchers and clinicians lies in their ability to provide precise genetic manipulation tools for investigating the biology of SAC3D1, ultimately contributing to the development of targeted therapies and enhancing our comprehension of gene function in health and disease.
As a leader in the biotechnology industry, our company specializes in the production of high-quality genetic models, backed by extensive expertise in molecular biology techniques. We are committed to empowering researchers with the resources they need to drive impactful discoveries.
Please note that all services are for research use only. Not intended for any clinical use.
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