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S1PR2 Knockout Cell Lines

Gene: S1PR2

Official Full Name: sphingosine-1-phosphate receptor 2provided by HGNC

Gene Summary: This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. The encoded protein is a receptor for sphingosine 1-phosphate, which participates in cell proliferation, survival, and transcriptional activation. Defects in this gene have been associated with congenital profound deafness. [provided by RefSeq, Mar 2016]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO07603 S1PR2 Knockout cell line (HeLa) Human S1PR2 1:3~1:6 Negative Online Inquiry
KO07604 S1PR2 Knockout cell line (HCT 116) Human S1PR2 1:2~1:4 Negative Online Inquiry
KO07605 S1PR2 Knockout cell line (HEK293) Human S1PR2 1:3~1:6 Negative Online Inquiry

Background

S1PR2 Gene Knockout Cell Lines are specialized cellular models in which the S1PR2 gene, encoding the sphingosine-1-phosphate receptor 2, has been precisely inactivated. This groundbreaking tool enables researchers to investigate the multifaceted roles of S1PR2 in various physiological and pathological contexts. S1PR2 plays a crucial role in cell signaling pathways, influencing processes such as immune response, angiogenesis, and cell migration through its interactions with sphingosine-1-phosphate (S1P), a bioactive lipid.

The key functions of S1PR2 Knockout Cell Lines include the ability to elucidate the receptor's specific contributions to cellular behavior and signaling cascades in response to S1P gradients. By comparing the knockout models to wild-type cells, researchers can delineate the downstream effects of S1PR2 signaling on cellular functions such as proliferation, apoptosis, and inflammatory responses. This specificity in understanding S1PR2's role provides invaluable insights into its potential implications in diseases like cancer, cardiovascular disorders, and immune dysfunctions.

In research and clinical settings, S1PR2 Gene Knockout Cell Lines have significant value, serving as critical tools for drug discovery and development. They facilitate the screening of therapeutic compounds targeting S1PR2 signaling pathways, thus driving advancements in tailored therapies. The precision of gene knockout technology ensures reproducibility and reliability, setting these cell lines apart from traditional cell culture models and enhancing data integrity.

The advantages of utilizing S1PR2 Gene Knockout Cell Lines lie in their ability to provide targeted insights that are often not achievable with pharmacological inhibitors or RNA interference approaches. Their specificity allows for a clearer interpretation of results, which is particularly beneficial for researchers looking to publish high-impact findings. Additionally, the availability of these knockout cell lines allows clinicians and scientists to better model human diseases and predict treatment outcomes.

With a commitment to advancing biological research, our company specializes in developing and providing high-quality genetic models, including S1PR2 Gene Knockout Cell Lines. Our expertise in genetic manipulation and cell line development ensures that our products meet the highest standards of quality and reliability, supporting researchers in their quest for scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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