Gene: RUNDC1
Official Full Name: RUN domain containing 1provided by HGNC
Gene Summary: This gene encodes a protein that contains a RUN (RPIP8, UNC-14 and NESCA) domain and a coiled coil domain. The encoded protein may negatively regulate p53 transcriptional activity. This gene is a potential candidate gene for predisposition to glioma in humans. [provided by RefSeq, May 2017]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO23927 | RUNDC1 Knockout cell line (HeLa) | Human | RUNDC1 | 1:3~1:6 | Negative | Online Inquiry |
KO23928 | RUNDC1 Knockout cell line (HCT 116) | Human | RUNDC1 | 1:2~1:4 | Negative | Online Inquiry |
KO23929 | RUNDC1 Knockout cell line (HEK293) | Human | RUNDC1 | 1:3~1:6 | Negative | Online Inquiry |
KO23930 | RUNDC1 Knockout cell line (A549) | Human | RUNDC1 | 1:3~1:4 | Negative | Online Inquiry |
RUNDC1 Gene Knockout Cell Lines are specialized cellular models that have been meticulously engineered to ablate the RUNDC1 gene, a critical regulator of various cellular processes. These knockout cell lines serve as essential tools for researchers seeking to elucidate the biological functions of RUNDC1, investigate its roles in cellular signaling pathways, and assess its contributions to disease mechanisms.
The primary function of the RUNDC1 Gene Knockout Cell Lines lies in their ability to provide a controlled environment for observing the effects of the absence of RUNDC1 on cell behavior, proliferation, and signaling. Mechanistically, the loss of the RUNDC1 gene disrupts specific pathways that are vital for cell growth and differentiation, thereby serving as a valuable system to study the implications of RUNDC1 in cellular physiology and pathology.
In the research landscape, these cell lines hold significant importance, particularly in the context of cancer biology and therapeutic development. By using RUNDC1 knockout models, researchers can better understand how impaired RUNDC1 function may contribute to tumor development, resistance to therapies, or other pathological states. Additionally, they can facilitate the screening of potential drugs that target these pathways, hence proving invaluable in preclinical trials.
What sets RUNDC1 Gene Knockout Cell Lines apart from alternative models is their validated genetic modification and consistent performance across various experimental conditions. The specificity of the knockout ensures that researchers can draw robust conclusions without the confounding effects that might arise from incomplete gene inhibition.
For researchers, clinicians, and pharmaceutical companies engaged in cutting-edge biological studies, the RUNDC1 Gene Knockout Cell Lines present a reliable and sophisticated option for exploring gene function and therapeutic potential. These cell lines not only accelerate research timelines but also enhance the reproducibility and reliability of experimental outcomes.
Our company is dedicated to providing high-quality biological products and has a proven track record in the field of genetic engineering. With expertise in developing advanced cellular models, we empower the scientific community to push the boundaries of discovery and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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