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RPS6KB2 Knockout Cell Lines

Gene: RPS6KB2

Official Full Name: ribosomal protein S6 kinase B2provided by HGNC

Gene Summary: This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains a kinase catalytic domain and phosphorylates the S6 ribosomal protein and eukaryotic translation initiation factor 4B (eIF4B). Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation. [provided by RefSeq, Jan 2015]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO11495 RPS6KB2 Knockout cell line (HeLa) Human RPS6KB2 1:3~1:6 Negative Online Inquiry
KO11496 RPS6KB2 Knockout cell line (HCT 116) Human RPS6KB2 1:2~1:4 Negative Online Inquiry
KO11497 RPS6KB2 Knockout cell line (HEK293) Human RPS6KB2 1:3~1:6 Negative Online Inquiry
KO11498 RPS6KB2 Knockout cell line (A549) Human RPS6KB2 1:3~1:4 Negative Online Inquiry

Background

RPS6KB2 Gene Knockout Cell Lines are advanced biological tools specifically designed to facilitate the study of the RPS6KB2 gene, which encodes the ribosomal protein S6 kinase beta-2. This gene plays pivotal roles in various cellular processes, including growth regulation, protein synthesis, and response to nutrient availability. By employing precise gene-editing techniques such as CRISPR/Cas9, these knockout cell lines exhibit complete ablation of RPS6KB2 expression, enabling researchers to investigate the gene’s functions without the confounding influences of its normal activity.

The key mechanism behind RPS6KB2 Gene Knockout Cell Lines lies in their ability to create a controlled environment for studying gene function and cellular pathways involved in processes like mitogenesis and mTOR signaling. By providing a clear view of the consequences of RPS6KB2 loss, these cell lines allow scientists to elucidate signaling networks and biological ramifications linked to cancer, metabolic disorders, and other pathologies.

The scientific importance of RPS6KB2 knockout models extends across various research and clinical applications. They serve as invaluable tools for drug development, biomarker identification, and the exploration of disease mechanisms. In clinical settings, understanding the regulatory roles of RPS6KB2 can pave the way for targeted therapies and improved treatment options for patients with malignancies or metabolic syndromes.

What sets our RPS6KB2 Gene Knockout Cell Lines apart from alternatives in the market is the unparalleled specificity and reliability of our editing process. Each knockout line is characterized for mutation efficiency, off-target effects, and phenotypic stability, ensuring researchers obtain robust data with reproducible results. Moreover, our product comes with comprehensive technical support, including detailed protocols and expert consultations, making it easier for researchers to integrate these tools into their experimental designs.

Investing in RPS6KB2 Gene Knockout Cell Lines means equipping your research with cutting-edge resources to unlock new discoveries in gene function and disease mechanisms. Our company's commitment to advancing life sciences through high-quality biological products ensures that researchers and clinicians have the best possible tools at their disposal for innovative and impactful research.

Please note that all services are for research use only. Not intended for any clinical use.

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