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RPS6KB1 Knockout Cell Lines

Gene: RPS6KB1

Official Full Name: ribosomal protein S6 kinase B1provided by HGNC

Gene Summary: This gene encodes a member of the ribosomal S6 kinase family of serine/threonine kinases. The encoded protein responds to mTOR (mammalian target of rapamycin) signaling to promote protein synthesis, cell growth, and cell proliferation. Activity of this gene has been associated with human cancer. Alternatively spliced transcript variants have been observed. The use of alternative translation start sites results in isoforms with longer or shorter N-termini which may differ in their subcellular localizations. There are two pseudogenes for this gene on chromosome 17. [provided by RefSeq, Jan 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO11499 RPS6KB1 Knockout cell line (HeLa) Human RPS6KB1 1:3~1:6 Negative Online Inquiry
KO11500 RPS6KB1 Knockout cell line (HCT 116) Human RPS6KB1 1:2~1:4 Negative Online Inquiry
KO11501 RPS6KB1 Knockout cell line (HEK293) Human RPS6KB1 1:3~1:6 Negative Online Inquiry
KO11502 RPS6KB1 Knockout cell line (A549) Human RPS6KB1 1:3~1:4 Negative Online Inquiry

Background

RPS6KB1 Gene Knockout Cell Lines are specifically engineered biological tools that utilize advanced genetic editing techniques to disrupt the expression of the RPS6KB1 gene (also known as p70S6 kinase). This gene plays a crucial role in several cellular processes, including protein synthesis, cell growth, and metabolism, making it a target of significant interest in both basic and applied research. By creating knockout cell lines, researchers can study the function of the RPS6KB1 gene in isolation, allowing for a deeper understanding of its role in various cellular pathways and its implications in diseases, such as cancer and metabolic disorders.

The key function of these knockout cell lines lies in their ability to eliminate the gene's expression, enabling researchers to investigate downstream signaling events and phenotypic changes resulting from the loss of RPS6KB1 activity. This can illuminate pathways involving mTOR signaling and cellular responses to growth factors, as well as assess the impact of RPS6KB1 on cell proliferation and survival.

In scientific research and clinical settings, RPS6KB1 Gene Knockout Cell Lines serve a pivotal role in drug development and therapeutic strategies. Understanding how RPS6KB1 influences tumorigenesis or resistance to therapeutics can guide the design of more effective treatment protocols. Furthermore, these cell lines provide a robust platform for screening potential inhibitors and studying their efficacy in selective targeting.

What sets RPS6KB1 Gene Knockout Cell Lines apart from alternative models is their precision and reproducibility. Unlike transient transfection methods that may yield variable results, these stable, knockout lines ensure consistent gene disruption across experiments, enhancing the reliability of experimental outcomes.

For researchers and clinicians engaged in molecular biology, cancer research, and drug discovery, the value of RPS6KB1 Gene Knockout Cell Lines cannot be overstated. They represent an invaluable resource for elucidating gene function, assessing therapeutic responses, and developing targeted treatments. Our company specializes in providing top-quality genetic models and tools, backed by extensive expertise in biotechnological advancements. Through our commitment to high standards and innovative solutions, we empower scientists to advance their research with confidence.

Please note that all services are for research use only. Not intended for any clinical use.

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