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RPS6KA5 Knockout Cell Lines

Gene: RPS6KA5

Official Full Name: ribosomal protein S6 kinase A5provided by HGNC

Gene Summary: Enables ATP binding activity and protein kinase activity. Involved in several processes, including interleukin-1-mediated signaling pathway; protein modification process; and regulation of DNA-templated transcription. Located in cytoplasm and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO10487 RPS6KA5 Knockout cell line (HeLa) Human RPS6KA5 1:3~1:6 Negative Online Inquiry
KO10488 RPS6KA5 Knockout cell line (HCT 116) Human RPS6KA5 1:2~1:4 Negative Online Inquiry
KO10489 RPS6KA5 Knockout cell line (HEK293) Human RPS6KA5 1:3~1:6 Negative Online Inquiry
KO10490 RPS6KA5 Knockout cell line (A549) Human RPS6KA5 1:3~1:4 Negative Online Inquiry

Background

RPS6KA5 Gene Knockout Cell Lines are specialized human cell lines engineered to lack the expression of the RPS6KA5 gene, which encodes for ribosomal protein S6 kinase alpha-5, a critical regulator of cellular signaling pathways involved in growth, proliferation, and survival. By utilizing CRISPR/Cas9 gene editing technology, these cell lines facilitate the study of RPS6KA5's role in various biological processes and disease states, particularly in cancer research and metabolic disorders.

The primary function of RPS6KA5 is to modulate the mitogen-activated protein kinase (MAPK) signaling pathway, influencing cell growth and differentiation. The knockout of this gene allows researchers to dissect its contributions to cellular responses, revealing insights into mechanistic pathways underlying diseases and providing a powerful tool for drug development. Understanding how this kinase interacts with other molecular players helps delineate pathways that could be targeted therapeutically.

In scientific research and clinical applications, the RPS6KA5 Gene Knockout Cell Lines hold significant importance. They enable the exploration of the gene's implications in cancers where aberrant signaling pathways are prevalent. This cell line model is instrumental for phenotypic characterization, high-throughput screening, and further elucidation of cancer biology, leading to the identification of potential biomarkers and therapeutic targets.

Compared to alternatives, the RPS6KA5 Gene Knockout Cell Lines offer a precise gene alteration, allowing for controlled experimental conditions and reproducibility. These lines provide a unique opportunity to study the effects of RPS6KA5 loss-of-function in a variety of cellular contexts, surpassing traditional models that may not capture the intricate behavior of human cells in relation to this gene.

For researchers and clinicians, the ability to utilize these knockout cell lines accelerates advancements in the understanding of complex diseases and fosters innovations in targeted therapies. Our company is committed to providing high-quality biological products, leveraging our expertise in genetic engineering to support cutting-edge research. By offering RPS6KA5 Gene Knockout Cell Lines, we aim to empower the scientific community to achieve their research goals with precision and reliability.

Please note that all services are for research use only. Not intended for any clinical use.

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