Gene: RIPK4
Official Full Name: receptor interacting serine/threonine kinase 4provided by HGNC
Gene Summary: The protein encoded by this gene is a serine/threonine protein kinase that interacts with protein kinase C-delta. The encoded protein can also activate NFkappaB and is required for keratinocyte differentiation. This kinase undergoes autophosphorylation. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO05076 | RIPK4 Knockout cell line (HeLa) | Human | RIPK4 | 1:3~1:6 | Negative | Online Inquiry |
KO05077 | RIPK4 Knockout cell line (HCT 116) | Human | RIPK4 | 1:2~1:4 | Negative | Online Inquiry |
KO05078 | RIPK4 Knockout cell line (HEK293) | Human | RIPK4 | 1:3~1:6 | Negative | Online Inquiry |
KO05079 | RIPK4 Knockout cell line (A549) | Human | RIPK4 | 1:3~1:4 | Negative | Online Inquiry |
RIPK4 Gene Knockout Cell Lines are genetically engineered cell lines that have had the RIPK4 gene inactivated, allowing researchers to study the functional implications of this gene's loss on cellular processes. The receptor-interacting protein kinase 4 (RIPK4) is crucial for several signal transduction pathways that regulate cell survival, proliferation, and inflammation. By creating knockout models, researchers can investigate the mechanisms by which RIPK4 influences these cellular functions, thereby uncovering its role in various diseases, including cancer and inflammatory disorders.
The primary function of these cell lines lies in their ability to provide insights into the signaling cascades affected by the absence of RIPK4. By utilizing techniques such as Western blotting, qPCR, or RNA sequencing, scientists can assess changes in downstream effectors, apoptosis, or cellular response to external stimuli. This research is particularly important for understanding the tumorigenic potential associated with altered RIPK4 activity, which can open new avenues for therapeutic intervention.
What sets RIPK4 Gene Knockout Cell Lines apart from other gene-modified models is their precise genetic editing, achieved using CRISPR-Cas9 technology, ensuring complete and reproducible gene inactivation. This precision allows for consistent experimental results, making it easier for researchers to draw conclusions from their studies. In addition, the use of these specific cell lines enables tailored experimental setups that facilitate the exploration of context-specific pathways influenced by RIPK4.
For clinicians and researchers, the value of utilizing RIPK4 knockout models lies in their potential to accelerate the understanding of complex biological systems and the identification of novel therapeutic targets. By providing an innovative tool for studying gene function, these cell lines empower researchers to translate basic scientific findings into clinical applications.
Additionally, our company boasts extensive expertise in cellular and molecular biology products, ensuring that you receive high-quality and reliable tools for your research needs. Our commitment to scientific advancement ensures that our RIPK4 Gene Knockout Cell Lines will remain at the cutting edge of biological research.
Please note that all services are for research use only. Not intended for any clinical use.
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