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RIC8B Knockout Cell Lines

Gene: RIC8B

Official Full Name: RIC8 guanine nucleotide exchange factor Bprovided by HGNC

Gene Summary: Enables G-protein alpha-subunit binding activity. Acts upstream of or within regulation of G protein-coupled receptor signaling pathway. Located in centrosome; cytosol; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14540 RIC8B Knockout cell line (HeLa) Human RIC8B 1:3~1:6 Negative Online Inquiry
KO14541 RIC8B Knockout cell line (HCT 116) Human RIC8B 1:2~1:4 Negative Online Inquiry
KO14542 RIC8B Knockout cell line (HEK293) Human RIC8B 1:3~1:6 Negative Online Inquiry
KO14543 RIC8B Knockout cell line (A549) Human RIC8B 1:3~1:4 Negative Online Inquiry

Background

RIC8B Gene Knockout Cell Lines are advanced biological tools specifically engineered to facilitate the study of gene function and regulation in mammalian cells. Using cutting-edge CRISPR/Cas9 technology, these cell lines have been meticulously developed to exhibit precise deletions in the RIC8B gene, allowing researchers to investigate the biological implications of its absence. RIC8B is known to play a crucial role in the regulation of G protein signaling, influencing numerous cellular processes and pathways.

The key function of RIC8B knockout cell lines lies in their ability to serve as a model for investigating the effects of disrupted G protein signaling. By examining the phenotypic and biochemical changes that occur in these cell lines, scientists can unravel complex signaling pathways and their associated biological responses. This knowledge is vital for understanding various diseases, including cancer and neurodegenerative disorders, where G protein signaling is often altered.

The scientific importance of RIC8B gene knockout cell lines cannot be overstated, as they provide a robust platform for drug discovery, functional genomic studies, and therapeutic target validation. Their applications extend to both basic research and clinical settings, where they aid in the identification of potential biomarkers and therapeutic agents.

What sets RIC8B gene knockout cell lines apart from alternative products is the precision with which they have been created, coupled with the extensive characterization data provided. Researchers benefit from our proprietary screening protocols that ensure high reproducibility, as well as optimized growth conditions, allowing for efficient experimental design.

For researchers and clinicians alike, the value of utilizing RIC8B gene knockout cell lines lies in their ability to substantially advance the understanding of G protein-coupled receptor signaling and related pathways. This, in turn, supports the development of innovative therapeutic strategies to tackle a range of diseases.

With a commitment to excellence and innovation, our company specializes in providing high-quality biological products, including RIC8B gene knockout cell lines, backed by years of expertise in genetic engineering and cell biology. Our offerings empower the global scientific community to drive breakthroughs in research and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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