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RHBDL1 Knockout Cell Lines

Gene: RHBDL1

Official Full Name: rhomboid like 1provided by HGNC

Gene Summary: This gene encodes a protein similar to Rhomboid in Drosophila which is involved in signalling in the Spitz/epidermal growth factor receptor/mitogen-activated protein kinase pathway. The Rhomboid family of proteins consists of intramembrane serine proteases containing several transmembrane domains. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2013]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO33641 RHBDL1 Knockout cell line (HeLa) Human RHBDL1 1:3~1:6 Negative Online Inquiry
KO33642 RHBDL1 Knockout cell line (HCT 116) Human RHBDL1 1:2~1:4 Negative Online Inquiry
KO33643 RHBDL1 Knockout cell line (HEK293) Human RHBDL1 1:3~1:6 Negative Online Inquiry

Background

RHBDL1 Gene Knockout Cell Lines are genetically engineered cell lines specifically designed to facilitate the study of the Rhomboid-like 1 (RHBDL1) gene's role in cellular processes. These cell lines feature precise deletions of the RHBDL1 gene, providing researchers with a powerful tool to investigate its involvement in various biological pathways and disease mechanisms. By removing the functional alleles of RHBDL1, scientists can assess the resulting phenotypic changes, signaling pathways, and intracellular interactions, offering insights into the gene's contributions to cellular homeostasis and pathology.

The key function of these knockout cell lines lies in their ability to serve as a control system for elucidating RHBDL1's role in the regulation of proteolytic processes. RHBDL1 is known to be involved in the regulation of protein degradation and has implications in diverse conditions, including cancer and neurodegenerative disorders. By utilizing RHBDL1 knockout cell lines, researchers can observe how the absence of this gene affects cell viability, proliferation, and response to external stimuli, which could lead to breakthroughs in understanding diseases where RHBDL1 is a critical player.

In the scientific community, the availability of RHBDL1 knockout cell lines holds particular significance for both basic and applied research. In clinical settings, these cell lines can help in the development of targeted therapies aimed at diseases linked to RHBDL1 dysregulation. The nuances of gene function revealed through these models can facilitate not only fundamental biology research but also the translational aspects of drug discovery.

What sets our RHBDL1 Gene Knockout Cell Lines apart from alternative products is the precision of our genetic editing techniques and the quality of our cell culture protocols. Our knockout lines are validated through rigorous genomic assays, ensuring that researchers receive reliable and reproducible results. Furthermore, our comprehensive support services and detailed product documentation make these cell lines particularly user-friendly for both novice and experienced researchers.

Investing in RHBDL1 Gene Knockout Cell Lines provides a strategic advantage to researchers and clinicians looking to deepen their understanding of RHBDL1-related mechanisms, leading to potential innovations in therapeutic approaches. Our company prides itself on its expertise in the development of high-quality biological products, ensuring that our customers have access to cutting-edge tools that propel their research forward.

Please note that all services are for research use only. Not intended for any clinical use.

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