Gene: REEP5
Official Full Name: receptor accessory protein 5provided by HGNC
Gene Summary: Predicted to be involved in endoplasmic reticulum membrane organization and regulation of intracellular transport. Located in endoplasmic reticulum tubular network. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO03333 | REEP5 Knockout cell line (HeLa) | Human | REEP5 | 1:3~1:6 | Negative | Online Inquiry |
KO03334 | REEP5 Knockout cell line (HCT 116) | Human | REEP5 | 1:2~1:4 | Negative | Online Inquiry |
KO03335 | REEP5 Knockout cell line (HEK293) | Human | REEP5 | 1:3~1:6 | Negative | Online Inquiry |
KO03336 | REEP5 Knockout cell line (A549) | Human | REEP5 | 1:3~1:4 | Negative | Online Inquiry |
REEP5 Gene Knockout Cell Lines are specialized cellular models engineered to lack the REEP5 gene, which is implicated in various cellular functions, particularly in the context of endoplasmic reticulum (ER) morphology and function. These knockout cell lines allow researchers to investigate the role of REEP5 in cellular processes such as protein folding, trafficking, and overall endoplasmic reticulum homeostasis. The knockout mechanism is typically achieved through CRISPR-Cas9 technology, ensuring precise gene editing and reliable loss-of-function characteristics.
The primary function of REEP5 involves the modulation of the shaping of the ER, a crucial organelle involved in lipid synthesis and protein maturation. By studying the REEP5 knockout cell lines, researchers can elucidate the gene’s function in specific stress responses, its involvement in neurodegenerative diseases, and potential links to metabolic disorders. Such insights are vital for untangling complex biological pathways that underpin disease mechanisms, offering opportunities for developing targeted therapies and interventions.
What sets REEP5 Gene Knockout Cell Lines apart from traditional cell models is their specificity and reliability. Unlike conventional knockdown strategies that may retain residual gene expression, these knockout lines completely abolish REEP5 activity, providing clearer insights into gene function. This specificity enhances experimental reproducibility and reduces variability, important attributes for rigorous scientific research.
For researchers and clinicians focused on the intersection of cellular biology and therapeutic development, REEP5 Gene Knockout Cell Lines represent an invaluable tool, offering a way to investigate gene function in contexts that are highly relevant to human health. With their precision-engineered design, these cell lines can empower groundbreaking discoveries leading to innovative treatments.
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Please note that all services are for research use only. Not intended for any clinical use.
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