Gene: REEP3
Official Full Name: receptor accessory protein 3provided by HGNC
Gene Summary: Predicted to enable microtubule binding activity. Involved in mitotic nuclear membrane reassembly. Predicted to be located in endoplasmic reticulum; membrane; and microtubule. Predicted to be active in cytoplasmic microtubule; endoplasmic reticulum membrane; and endoplasmic reticulum tubular network. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO27569 | REEP3 Knockout cell line (HeLa) | Human | REEP3 | 1:3~1:6 | Negative | Online Inquiry |
KO27570 | REEP3 Knockout cell line (HCT 116) | Human | REEP3 | 1:2~1:4 | Negative | Online Inquiry |
KO27571 | REEP3 Knockout cell line (HEK293) | Human | REEP3 | 1:3~1:6 | Negative | Online Inquiry |
KO27572 | REEP3 Knockout cell line (A549) | Human | REEP3 | 1:3~1:4 | Negative | Online Inquiry |
REEP3 Gene Knockout Cell Lines are advanced cellular models specifically engineered to lack the REEP3 gene. This gene, known for its role in endoplasmic reticulum (ER) morphology and function, has become pivotal in research focused on cellular stress responses, neurodegeneration, and other pathophysiological conditions. The knockout of the REEP3 gene allows researchers to investigate the consequences of its absence, unraveling the cellular pathways that rely on this gene's protein product.
The primary function of these cell lines is to facilitate the examination of REEP3's involvement in maintaining ER structure, as well as its impact on protein folding and trafficking. By employing CRISPR/Cas9 technology, these knockout cell lines exhibit precise genetic modifications that offer a reliable tool to dissect the roles of REEP3 during ER stress conditions and in the development of neurodegenerative diseases. The elimination of REEP3 enables researchers to study the compensatory mechanisms cells may activate in response to the loss of this critical gene.
The scientific importance of REEP3 Gene Knockout Cell Lines is particularly pronounced in the study of diseases such as Alzheimer's, where ER stress and protein misfolding contribute to disease pathology. Additionally, in clinical settings, understanding REEP3 functions may lead to novel therapeutic approaches for managing these disorders, offering hope for targeted treatments.
What sets our REEP3 Gene Knockout Cell Lines apart from alternatives is their high specificity and reproducibility, ensuring that experimental results are reliable and applicable across various research contexts. These cell lines feature robust documentation and characterization data, providing users with confidence in their experimental designs and potential findings.
For researchers and clinicians alike, the value of these cell lines lies not only in their ability to elucidate the biological mechanisms behind cellular dysfunction but also in their potential to pave the way for innovative therapies. By investing in our REEP3 Gene Knockout Cell Lines, practitioners gain access to a powerful research tool that enhances their investigational capabilities.
In addition, our company boasts extensive expertise in developing cutting-edge biological products that meet rigorous research demands. We are committed to supporting the scientific community by delivering high-quality, validated tools that drive discovery and innovation.
Please note that all services are for research use only. Not intended for any clinical use.
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