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RDX Knockout Cell Lines

Gene: RDX

Official Full Name: radixinprovided by HGNC

Gene Summary: Radixin is a cytoskeletal protein that may be important in linking actin to the plasma membrane. It is highly similar in sequence to both ezrin and moesin. The radixin gene has been localized by fluorescence in situ hybridization to 11q23. A truncated version representing a pseudogene (RDXP2) was assigned to Xp21.3. Another pseudogene that seemed to lack introns (RDXP1) was mapped to 11p by Southern and PCR analyses. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO03066 RDX Knockout cell line (HeLa) Human RDX 1:3~1:6 Negative Online Inquiry
KO03067 RDX Knockout cell line (HCT 116) Human RDX 1:2~1:4 Negative Online Inquiry
KO03068 RDX Knockout cell line (HEK293) Human RDX 1:3~1:6 Negative Online Inquiry
KO03069 RDX Knockout cell line (A549) Human RDX 1:3~1:4 Negative Online Inquiry

Background

RDX Gene Knockout Cell Lines are specifically engineered cellular models designed to facilitate the study of the RDX gene's role in cellular processes and disease mechanisms. Utilizing advanced CRISPR-Cas9 gene editing technology, these cell lines allow for precise knockout of the RDX gene, enabling researchers to investigate the implications of its absence on cellular function, signaling pathways, and phenotypic expression.

The key mechanism behind these cell lines lies in the targeted disruption of the RDX gene, which encodes for an essential protein that participates in the regulation of cellular dynamics and stress responses. By observing how these knockout models behave under various experimental conditions, scientists can elucidate the biological pathways in which RDX is implicated, thus providing a deeper understanding of its potential as a therapeutic target in diseases such as cancer, neurodegenerative disorders, and others.

The scientific importance of RDX Gene Knockout Cell Lines is underscored by their wide applicability in both basic and translational research settings. In vitro studies utilizing these models can yield insights into gene function and assist in the development of novel gene therapies, making them invaluable to academic and industrial laboratories alike.

Compared to conventional gene knockout methodologies, RDX Gene Knockout Cell Lines offer significant advantages, including enhanced specificity, reduced off-target effects, and the ready availability of well-characterized lines. This streamlines research workflows and accelerates discovery timelines, thus representing a cost-effective alternative for researchers aiming for precision and reproducibility in their experiments.

For researchers and clinicians, utilizing RDX Gene Knockout Cell Lines translates to high-quality data and insights that can propel the understanding of disease mechanisms and facilitate the identification of therapeutic targets. Our company prides itself on expertise in developing cutting-edge biological products backed by rigorous scientific validation, ensuring that users have access to reliable and impactful research tools to advance their scientific endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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