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RCOR3 Knockout Cell Lines

Gene: RCOR3

Official Full Name: REST corepressor 3provided by HGNC

Gene Summary: Predicted to enable enzyme binding activity and transcription corepressor activity. Predicted to be involved in negative regulation of DNA-templated transcription and regulation of transcription by RNA polymerase II. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14632 RCOR3 Knockout cell line (HeLa) Human RCOR3 1:3~1:6 Negative Online Inquiry
KO14633 RCOR3 Knockout cell line (HCT 116) Human RCOR3 1:2~1:4 Negative Online Inquiry
KO14634 RCOR3 Knockout cell line (HEK293) Human RCOR3 1:3~1:6 Negative Online Inquiry
KO14635 RCOR3 Knockout cell line (A549) Human RCOR3 1:3~1:4 Negative Online Inquiry

Background

RCOR3 Gene Knockout Cell Lines are a state-of-the-art biological tool designed for researchers investigating the functional role of the RCOR3 gene in various cellular processes. These genetically modified cell lines have been created using CRISPR-Cas9 technology, a highly precise and efficient gene-editing method that enables the targeted disruption of specific genomic sequences. By knocking out the RCOR3 gene, researchers can elucidate the gene's contributions to tissue development, neural function, and its implications in certain pathologies, including cancer and neurodegenerative disorders.

The key function of RCOR3 Gene Knockout Cell Lines lies in their ability to serve as a model system for understanding gene function and interactions. This gene is known to be involved in the regulation of several transcription factors, thus playing a critical role in gene expression pathways and epigenetic modifications. By utilizing these knockout cell lines, scientists can analyze downstream effects on cellular signaling, proliferation, and differentiation under controlled experimental conditions.

The scientific significance of these cell lines extends to both research and clinical settings. In research laboratories, they provide invaluable insights into gene function and disease mechanisms, potentially leading to novel therapeutic targets. Clinically, the ability to model specific genetic disruptions paves the way for drug discovery and testing, particularly in diseases where RCOR3 has been implicated.

Compared to alternative models that may include whole organisms or less specific cell lines, RCOR3 Gene Knockout Cell Lines offer a higher degree of accuracy and reproducibility. The targeted nature of the knockout reduces off-target effects, enabling researchers to obtain clearer and more reliable data.

For researchers and clinicians focused on genetics, developmental biology, or pathology, these cell lines represent a powerful asset in the advancement of biomedical knowledge. They are ideally suited for both basic and translational research efforts due to their ability to mimic human cellular responses with fidelity. Our company, recognized for expertise in cutting-edge genetic models, is committed to providing high-quality, user-friendly products that facilitate groundbreaking discoveries in the life sciences.

Please note that all services are for research use only. Not intended for any clinical use.

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