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RCN2 Knockout Cell Lines

Gene: RCN2

Official Full Name: reticulocalbin 2provided by HGNC

Gene Summary: The protein encoded by this gene is a calcium-binding protein located in the lumen of the ER. The protein contains six conserved regions with similarity to a high affinity Ca(+2)-binding motif, the EF-hand. This gene maps to the same region as type 4 Bardet-Biedl syndrome, suggesting a possible causative role for this gene in the disorder. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2012]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO07141 RCN2 Knockout cell line (HeLa) Human RCN2 1:3~1:6 Negative Online Inquiry
KO07142 RCN2 Knockout cell line (HCT 116) Human RCN2 1:2~1:4 Negative Online Inquiry
KO07143 RCN2 Knockout cell line (HEK293) Human RCN2 1:3~1:6 Negative Online Inquiry
KO07144 RCN2 Knockout cell line (A549) Human RCN2 1:3~1:4 Negative Online Inquiry

Background

RCN2 Gene Knockout Cell Lines are specialized cell lines in which the RCN2 gene has been selectively disrupted or "knocked out" using advanced gene-editing techniques such as CRISPR-Cas9. The RCN2 gene encodes for the protein reticulocalbin 2, which plays a critical role in calcium homeostasis and protein folding in the endoplasmic reticulum. By creating a knockout of this gene, researchers can effectively investigate the functional consequences of RCN2 loss, examining pathways involved in intracellular signaling, apoptosis, and cellular stress responses.

The primary function of RCN2 Gene Knockout Cell Lines is to serve as an innovative tool for elucidating the mechanisms behind various biological processes and disease states. When RCN2 is absent, cellular response mechanisms to stress and calcium regulation can be thoroughly studied, providing insights that could lead to the identification of therapeutic targets in diseases like cancer, neurodegeneration, and cardiovascular disorders. The significance of this product extends to both research and clinical settings, as these cell lines enable scientists and clinicians to replicate human disease models more accurately and screen potential drug candidates effectively.

One of the key advantages of RCN2 Gene Knockout Cell Lines is their specificity and reproducibility in experimental design. Unlike alternative models such as animal studies, these cell lines allow for precise control over genetic variables and reduce biological variability. Moreover, they can be easily manipulated to create additional genetic modifications, enabling comprehensive functional studies. Such versatility is invaluable in a research environment, ensuring that users can derive meaningful data that informs their hypotheses and experimental outcomes.

The value of RCN2 Gene Knockout Cell Lines to researchers and clinicians lies in their ability to streamline research processes while delivering high-quality, relevant data. Institutions invested in cellular biology, pharmacology, and therapeutic development will find this product particularly beneficial for advancing their research agendas. With a commitment to quality and innovation, our company stands as a leader in providing cutting-edge biological products, ensuring researchers have access to reliable tools that push the boundaries of science. By incorporating RCN2 Gene Knockout Cell Lines into their work, users can leverage the latest advancements in gene editing to drive impactful discoveries and clinical applications.

Please note that all services are for research use only. Not intended for any clinical use.

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