Home / RC3H1 Knockout Cell Lines

RC3H1 Knockout Cell Lines

Gene: RC3H1

Official Full Name: ring finger and CCCH-type domains 1provided by HGNC

Gene Summary: This gene encodes a protein containing RING-type and C3H1-type zinc finger motifs. The encoded protein recognizes and binds to a constitutive decay element (CDE) in the 3' UTR of mRNAs, leading to mRNA deadenylation and degradation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

Get A Quote
Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO23010 RC3H1 Knockout cell line (HeLa) Human RC3H1 1:3~1:6 Negative Online Inquiry
KO23011 RC3H1 Knockout cell line (HCT 116) Human RC3H1 1:2~1:4 Negative Online Inquiry
KO23012 RC3H1 Knockout cell line (HEK293) Human RC3H1 1:3~1:6 Negative Online Inquiry
KO23013 RC3H1 Knockout cell line (A549) Human RC3H1 1:3~1:4 Negative Online Inquiry

Background

RC3H1 Gene Knockout Cell Lines are specialized cellular models engineered to lack the RC3H1 gene, which encodes a zinc-finger RNA-binding protein pivotal in regulating mRNA turnover and gene expression. By effectively knocking out this gene, these cell lines allow researchers to assess the functional implications of RC3H1 depletion on various cellular processes, including RNA stability, cellular response to stress, and gene regulatory networks.

The key functions of these cell lines lie in their ability to mimic conditions of gene repression and facilitate the study of downstream effects related to this modification. Through loss-of-function studies, scientists can explore how disrupted RC3H1 expression influences pathways involved in mRNA degradation and translation, potentially illuminating mechanisms involved in diseases where altered RNA metabolism plays a critical role.

The scientific importance of RC3H1 Gene Knockout Cell Lines extends to various research and clinical applications. They are particularly valuable in investigating neurodegenerative diseases, cancer biology, and developmental processes, where RNA dynamics are crucial. Additionally, they serve as an excellent platform for testing therapeutic interventions targeting RNA metabolism.

A significant advantage of using our RC3H1 Gene Knockout Cell Lines over traditional models lies in their precise genetic modification, ensuring a reproducible and reliable study of the effects of RC3H1 deletion. This specificity reduces variability and enhances the overall integrity of experimental results, empowering researchers to derive more conclusive findings.

For researchers and clinicians striving for precision in studying gene function and RNA regulation, these cell lines represent a highly versatile tool. With the mounting evidence linking RNA-binding proteins to critical health conditions, the availability of RC3H1 knockout models aligns with the urgent need for innovative approaches in biomedical research.

Our commitment to advancing scientific exploration is reflected in our extensive expertise in developing targeted cellular models. We are dedicated to providing cutting-edge resources that empower the research community to unravel the complexities of gene function and its implications in health and disease.

Please note that all services are for research use only. Not intended for any clinical use.

Get a free quote

If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.

0

There is no product in your cart.