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RBMS2 Knockout Cell Lines

Gene: RBMS2

Official Full Name: RNA binding motif single stranded interacting protein 2provided by HGNC

Gene Summary: The protein encoded by this gene is a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. The RBMS proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. This protein was isolated by phenotypic complementation of cdc2 and cdc13 mutants of yeast and is thought to suppress cdc2 and cdc13 mutants through the induction of translation of cdc2. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35672 RBMS2 Knockout cell line (HeLa) Human RBMS2 1:3~1:6 Negative Online Inquiry
KO35673 RBMS2 Knockout cell line (HCT 116) Human RBMS2 1:2~1:4 Negative Online Inquiry
KO35674 RBMS2 Knockout cell line (HEK293) Human RBMS2 1:3~1:6 Negative Online Inquiry
KO35675 RBMS2 Knockout cell line (A549) Human RBMS2 1:3~1:4 Negative Online Inquiry

Background

RBMS2 Gene Knockout Cell Lines are specialized cellular models engineered to lack the RBMS2 gene, which plays a critical role in various cellular processes, including RNA binding, transcriptional regulation, and cell cycle control. These knockout cell lines serve as essential tools for researchers investigating the multifaceted functions of the RBMS2 gene and its implications in disease mechanisms, such as cancer and neurodegenerative disorders.

The primary function of the RBMS2 knockout model involves creating a controlled environment that allows comprehensive studies on the downstream effects of RBMS2 loss. By employing CRISPR-Cas9 or other gene-editing technologies, these cell lines exhibit a complete absence of the RBMS2 protein. This facilitates the exploration of its role in cellular communication, signal transduction pathways, and its contribution to the phenotypic traits of various cell types. Researchers can utilize these cell lines to assess cellular behaviors such as proliferation, differentiation, and apoptosis, thus providing insights into the pathological implications associated with RBMS2 dysregulation.

In scientific research, the RBMS2 knockout cell lines are invaluable for dissecting the molecular mechanisms underlying cancer development and progression. Their application extends to identifying therapeutic targets and elucidating cellular responses to treatment modalities. In a clinical context, these models allow the exploration of personalized medicine approaches by predicting patient responses based on the genetic status of RBMS2.

A significant advantage of our RBMS2 Gene Knockout Cell Lines is their rigorous validation through extensive characterization, ensuring reproducibility and reliability in experimental setups. Unlike alternative options that may lack specificity or demonstrate inconsistent results, our cell lines provide a consistent background for research, facilitating accurate comparisons across studies.

For researchers and clinicians aiming to unlock the complexities of gene function and its therapeutic implications, the RBMS2 Gene Knockout Cell Lines represent a strategic asset. They promote innovative discoveries in molecular biology and disease treatment strategies, making them a cornerstone tool in advanced genetic research.

Our company specializes in providing high-quality genetic models and reagents designed to empower scientific exploration and innovation. With our extensive expertise in gene editing technology and cell line development, we are committed to supporting the global research community with reliable, cutting-edge biological products.

Please note that all services are for research use only. Not intended for any clinical use.

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