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RBMS1 Knockout Cell Lines

Gene: RBMS1

Official Full Name: RNA binding motif single stranded interacting protein 1provided by HGNC

Gene Summary: This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12. [provided by RefSeq, Feb 2009]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35676 RBMS1 Knockout cell line (HeLa) Human RBMS1 1:3~1:6 Negative Online Inquiry
KO35677 RBMS1 Knockout cell line (HCT 116) Human RBMS1 1:2~1:4 Negative Online Inquiry
KO35678 RBMS1 Knockout cell line (HEK293) Human RBMS1 1:3~1:6 Negative Online Inquiry
KO35679 RBMS1 Knockout cell line (A549) Human RBMS1 1:3~1:4 Negative Online Inquiry

Background

RBMS1 Gene Knockout Cell Lines are genetically engineered human cell lines wherein the RBMS1 gene has been selectively disrupted through advanced CRISPR-Cas9 technology. RBMS1, or RNA-Binding Motif Single-Stranded Interacting Protein 1, plays critical roles in various cellular processes, particularly in RNA metabolism, cell signaling, and development. By utilizing RBMS1 knockout models, researchers can elucidate the functional consequences of loss-of-function mutations pertinent to cancer biology, neurobiology, and developmental research.

These cell lines operate by allowing researchers to study the downstream effects of RBMS1 deficiency on cellular pathways and gene expression profiles. The knockout of RBMS1 can lead to altered cell proliferation, differentiation, and survival, which are crucial parameters for understanding the mechanisms underlying various diseases. Additionally, researchers can investigate the RBMS1 interaction with other proteins and RNAs, thereby providing deep insights into cellular regulatory networks.

The scientific importance of RBMS1 Gene Knockout Cell Lines extends to both research and clinical settings. In academic and pharmaceutical laboratories, these models facilitate novel discovery pathways for therapeutic interventions targeting RBMS1-related malfunctions. They hold potential applications in personalized medicine, enabling the identification of biomarkers and therapeutic targets in cancers characterized by RBMS1 aberrations.

One significant advantage of our RBMS1 Gene Knockout Cell Lines is their high fidelity and reproducibility, resulting from rigorous validation processes. Unlike other alternatives such as transient gene silencing techniques, which can yield inconsistent results, these stable knockout models provide a robust platform for longitudinal studies and therapeutic screenings.

We believe that these cell lines are invaluable assets for researchers and clinicians seeking to deepen their understanding of RBMS1 functions and its implications in health and disease. Our commitment to precision in biotechnology ensures that every product we offer, including our RBMS1 Gene Knockout Cell Lines, is backed by extensive expertise and rigorous scientific validation, supporting your research endeavors with reliability and accuracy.

Please note that all services are for research use only. Not intended for any clinical use.

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