Gene: RASIP1
Official Full Name: Ras interacting protein 1provided by HGNC
Gene Summary: Enables GTPase binding activity and protein homodimerization activity. Involved in several processes, including negative regulation of Rho protein signal transduction; negative regulation of metabolic process; and positive regulation of integrin activation. Located in cell-cell junction. Part of protein-containing complex. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14703 | RASIP1 Knockout cell line (HeLa) | Human | RASIP1 | 1:3~1:6 | Negative | Online Inquiry |
KO14704 | RASIP1 Knockout cell line (HEK293) | Human | RASIP1 | 1:3~1:6 | Negative | Online Inquiry |
RASIP1 Gene Knockout Cell Lines are specialized cellular models engineered to selectively disrupt the RASIP1 gene, a crucial player in cellular signaling pathways associated with vascular development and angiogenesis. These cell lines enable researchers to study the specific role of RASIP1 in various biological processes, including endothelial cell function, vascular morphogenesis, and pathophysiological conditions such as cancer and cardiovascular diseases.
The mechanism behind these knockout cell lines involves CRISPR-Cas9 technology, which provides a precise editing tool for gene disruption. By introducing specific guide RNAs that target the RASIP1 gene, researchers can achieve high efficiency in gene knockout, leading to the study of the resultant phenotypic changes. This offers invaluable insights into the gene's contribution to cell signaling and potential compensatory mechanisms that may arise from its absence.
Scientifically, RASIP1 Gene Knockout Cell Lines hold significant importance in research and clinical applications. They offer a platform for drug discovery, allowing scientists to evaluate the efficacy of therapeutic compounds that target vascular-related pathways. Additionally, understanding RASIP1's role in angiogenesis is pivotal for developing novel treatments for diseases characterized by abnormal blood vessel formation, such as tumors and retinopathy.
What sets RASIP1 Gene Knockout Cell Lines apart from alternative products is their unparalleled specificity and versatility. Unlike generic knockouts or overexpression systems, these cell lines permit direct investigation into the effects of RASIP1 loss on cellular behaviors, thereby providing clearer experimental outcomes. Furthermore, they are compatible with high-throughput screening methods, making them an efficient choice for large-scale studies.
For researchers and clinicians focusing on vascular biology, these cell lines are an essential asset. They facilitate deeper understanding of disease mechanisms and support the development of targeted therapies, ultimately advancing the field of regenerative medicine and therapeutic interventions.
Our company prides itself on its commitment to empowering scientific discovery through high-quality, innovative biological products. With a robust portfolio of gene-editing tools and cellular models, we are dedicated to supporting researchers in their quest for breakthroughs in health and disease.
Please note that all services are for research use only. Not intended for any clinical use.
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