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RAP2B Knockout Cell Lines

Gene: RAP2B

Official Full Name: RAP2B, member of RAS oncogene familyprovided by HGNC

Gene Summary: This intronless gene belongs to a family of RAS-related genes. The proteins encoded by these genes share approximately 50% amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between the RAP and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. Evidence suggests that this protein may be polyisoprenylated and palmitoylated. [provided by RefSeq, Jul 2008]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO35704 RAP2B Knockout cell line (HeLa) Human RAP2B 1:3~1:6 Negative Online Inquiry
KO35705 RAP2B Knockout cell line (HCT 116) Human RAP2B 1:2~1:4 Negative Online Inquiry
KO35706 RAP2B Knockout cell line (HEK293) Human RAP2B 1:3~1:6 Negative Online Inquiry
KO35707 RAP2B Knockout cell line (A549) Human RAP2B 1:3~1:4 Negative Online Inquiry

Background

RAP2B Gene Knockout Cell Lines are genetically engineered cellular models in which the RAP2B gene, known for its role in cellular signaling and actin cytoskeletal dynamics, has been inactivated or deleted. This line of research-grade cell lines is pivotal for studying the biological implications of RAP2B knockouts, including their effects on cell proliferation, differentiation, and intracellular signaling pathways.

The primary function of RAP2B within a cell involves its regulatory effects on various downstream signaling cascades. By modulating the activity of small GTPases, RAP2B influences processes such as vesicular trafficking, cytoskeletal reorganization, and gene expression. Utilizing cell lines lacking this gene provides researchers a unique opportunity to dissect its contributions to cellular behaviors, helping to elucidate pathways associated with diseases like cancer or neurodegenerative disorders.

In clinical and research settings, RAP2B Gene Knockout Cell Lines serve as valuable tools for drug discovery and development. They aid in screening potential therapeutic compounds targeting specific signaling pathways impaired in various diseases. Furthermore, these knockout cell lines allow for the systematic examination of RAP2B’s role in cellular responses to stress, environmental changes, and pharmacological agents, thus contributing to the broader understanding of cellular adaptations and dysfunctions.

Compared to alternative experimental models, such as wild-type cell lines or those employing transient knockdown approaches, RAP2B knockout cell lines present a more stable and long-lasting solution for studying gene function. This durability offers significant advantages in experimental reproducibility and data reliability, making it easier for researchers to draw consistent and meaningful conclusions.

The RAP2B Gene Knockout Cell Lines are indispensable resources for scientists and clinicians alike. Their use can accelerate advancements in therapeutic strategies and fundamental research, providing insights that could lead to the development of novel treatments for various diseases.

With a commitment to high-quality biotechnological solutions, our company leverages years of expertise in genetic engineering and cell line development, ensuring that every product we offer, including the RAP2B Gene Knockout Cell Lines, meets the rigorous standards required for impactful scientific exploration.

Please note that all services are for research use only. Not intended for any clinical use.

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