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RALGPS1 Knockout Cell Lines

Gene: RALGPS1

Official Full Name: Ral GEF with PH domain and SH3 binding motif 1provided by HGNC

Gene Summary: Enables guanyl-nucleotide exchange factor activity. Involved in regulation of Ral protein signal transduction. Predicted to be located in cytoplasm. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO32981 RALGPS1 Knockout cell line (HeLa) Human RALGPS1 1:3~1:6 Negative Online Inquiry
KO32982 RALGPS1 Knockout cell line (HCT 116) Human RALGPS1 1:2~1:4 Negative Online Inquiry
KO32983 RALGPS1 Knockout cell line (HEK293) Human RALGPS1 1:3~1:6 Negative Online Inquiry
KO32984 RALGPS1 Knockout cell line (A549) Human RALGPS1 1:3~1:4 Negative Online Inquiry

Background

RALGPS1 Gene Knockout Cell Lines are sophisticated, genetically engineered cell lines designed to facilitate the study of the RALGPS1 gene by providing a model for evaluating its functional role in various biological processes. These cell lines are created using CRISPR/Cas9 genome editing technology to achieve precise knockout of the RALGPS1 gene, allowing researchers to investigate the effects of its absence on cellular pathways, signaling mechanisms, and disease states.

The RALGPS1 protein plays a pivotal role in the regulation of Ral GTPases, which are involved in critical processes such as cell growth, differentiation, and tumorigenesis. By utilizing RALGPS1 Gene Knockout Cell Lines, scientists can explore the downstream effects of RALGPS1 disruption, facilitating research into its implications in cancer biology and metabolic disorders. The knockout cell lines enable functional studies through assays that assess cellular proliferation, migration, and other metabolic activities, thereby providing insight into gateway mechanisms that are crucial for therapeutic interventions.

One of the most significant advantages of RALGPS1 Gene Knockout Cell Lines lies in their specificity and reliability. Unlike transient knockdown methods that offer temporally limited results, these stable knockout lines provide a sustained model for long-term studies, significantly enhancing reproducibility and reducing variability often seen in experimental results. This durability ensures that researchers can make conclusive connections between RALGPS1 activity and broader biological phenomena.

The value of RALGPS1 Gene Knockout Cell Lines extends into both academic and clinical environments. For researchers, these cell lines serve as an essential tool for elucidating pathways that may serve as therapeutic targets, while clinicians may leverage the findings to inform personalized medicine approaches in treating related diseases.

With a commitment to advancing molecular biology, our company specializes in delivering high-quality genetic models tailored for cutting-edge research. The RALGPS1 Gene Knockout Cell Lines reflect our dedication to providing innovative solutions that empower scientists and clinicians alike in their quest for knowledge and improved patient outcomes.

Please note that all services are for research use only. Not intended for any clinical use.

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