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RAI14 Knockout Cell Lines

Gene: RAI14

Official Full Name: retinoic acid induced 14provided by HGNC

Gene Summary: Predicted to enable actin binding activity. Predicted to be involved in cell differentiation and spermatogenesis. Located in cytosol; fibrillar center; and nucleoplasm. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO28375 RAI14 Knockout cell line (HeLa) Human RAI14 1:3~1:6 Negative Online Inquiry
KO28376 RAI14 Knockout cell line (HCT 116) Human RAI14 1:2~1:4 Negative Online Inquiry
KO28377 RAI14 Knockout cell line (HEK293) Human RAI14 1:3~1:6 Negative Online Inquiry
KO28378 RAI14 Knockout cell line (A549) Human RAI14 1:3~1:4 Negative Online Inquiry

Background

RAI14 Gene Knockout Cell Lines are a specialized set of genetically engineered mammalian cells that have been modified to lack the expression of the RAI14 gene. This gene is implicated in several critical cellular processes, including cell proliferation, differentiation, and response to stressors, making it an essential focus for research in cancer biology, developmental studies, and regenerative medicine.

The key mechanism of these knockout cell lines involves CRISPR-Cas9 technology, which allows for precise deletion of the RAI14 gene, effectively producing a cellular environment that mimics the pathological conditions associated with RAI14 dysregulation. By observing the biological outcomes in these cell lines, researchers can elucidate the role of RAI14 in various signaling pathways and identify potential therapeutic targets.

The scientific importance of RAI14 Gene Knockout Cell Lines is underscored by their potential applications in both basic and translational research. In academic settings, they serve as a powerful tool for understanding gene function and associated cellular processes. In clinical research, they can facilitate the development of novel therapies, particularly in oncology, where targeting specific genetic alterations has become a cornerstone of personalized medicine.

What sets RAI14 Gene Knockout Cell Lines apart from alternative models is their specificity and fidelity in replicating the loss-of-function mutation seen in patient-derived tissues. Unlike other generalized knockout systems, these cell lines provide a highly relevant in vitro context for investigating the RAI14 gene's role, yielding more reliable and translationally relevant results.

For researchers and clinicians, RAI14 Gene Knockout Cell Lines present a valuable resource for advancing their studies and improving understanding of complex biological mechanisms. The precise genetic modification, coupled with our rigorous validation processes, ensures that users receive high-quality, reproducible cell lines.

Our company is committed to providing innovative biological products with a focus on genetic engineering and cell line development. With a team of experienced scientists and a robust research infrastructure, we are poised to support the scientific community in achieving meaningful breakthroughs.

Please note that all services are for research use only. Not intended for any clinical use.

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