Gene: RAB15
Official Full Name: RAB15, member RAS oncogene familyprovided by HGNC
Gene Summary: Predicted to enable GTP binding activity and GTPase activity. Involved in positive regulation of regulated secretory pathway. Located in cilium; endosome membrane; and perinuclear region of cytoplasm. [provided by Alliance of Genome Resources, Apr 2025]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO24066 | RAB15 Knockout cell line (HeLa) | Human | RAB15 | 1:3~1:6 | Negative | Online Inquiry |
KO24067 | RAB15 Knockout cell line (HCT 116) | Human | RAB15 | 1:2~1:4 | Negative | Online Inquiry |
KO24068 | RAB15 Knockout cell line (HEK293) | Human | RAB15 | 1:3~1:6 | Negative | Online Inquiry |
KO24069 | RAB15 Knockout cell line (A549) | Human | RAB15 | 1:3~1:4 | Negative | Online Inquiry |
RAB15 Gene Knockout Cell Lines are genetically modified cell lines designed to selectively disable the RAB15 gene, a member of the RAS oncogene family implicated in various cellular processes, including membrane trafficking and lysosomal function. This product offers researchers a powerful tool for studying the specific biological functions and molecular pathways associated with RAB15, contributing to a greater understanding of its role in cellular homeostasis and pathology.
The RAB15 knockout is achieved through advanced CRISPR-Cas9 gene editing technology, enabling precise and efficient gene disruption. By removing the RAB15 gene, these cell lines provide a model to investigate the resultant phenotypic changes, including alterations in endosomal dynamics and potential implications for diseases such as cancer and metabolic disorders. Researchers can utilize these knockouts to elucidate the gene’s role in intracellular signaling, protein sorting, and its involvement in immune responses, thereby expanding knowledge in both fundamental biology and translational research.
The scientific importance of RAB15 Gene Knockout Cell Lines is underscored by their application across multiple domains, including drug discovery, where understanding the genetic influences on drug response is critical. Compared to other gene editing methods, the CRISPR-Cas9 approach used here offers high specificity with minimal off-target effects, ensuring reliable and reproducible results. This precision is essential for researchers focused on dissecting the complexities of gene function and its impact on disease.
Moreover, the availability of these knockout cell lines represents a significant advantage for those in academia and industry, providing a standardized model that enhances the robustness of experimental findings. By integrating RAB15 knockout models into research protocols, users can expect more accurate insights into gene-related mechanisms, ultimately driving forward new therapeutic approaches.
At [Your Company Name], we specialize in cutting-edge genetic engineering solutions with a commitment to advancing biological research. Our RAB15 Gene Knockout Cell Lines exemplify our dedication to providing high-quality products that empower researchers and clinicians in their pursuit of scientific discovery.
Please note that all services are for research use only. Not intended for any clinical use.
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