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PXK Knockout Cell Lines

Gene: PXK

Official Full Name: PX domain containing serine/threonine kinase likeprovided by HGNC

Gene Summary: This gene encodes a phox (PX) domain-containing protein which may be involved in synaptic transmission and the ligand-induced internalization and degradation of epidermal growth factors. Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO14783 PXK Knockout cell line (HeLa) Human PXK 1:3~1:6 Negative Online Inquiry
KO14784 PXK Knockout cell line (HCT 116) Human PXK 1:2~1:4 Negative Online Inquiry
KO14785 PXK Knockout cell line (HEK293) Human PXK 1:3~1:6 Negative Online Inquiry
KO14786 PXK Knockout cell line (A549) Human PXK 1:3~1:4 Negative Online Inquiry

Background

PXK Gene Knockout Cell Lines are genetically modified cell lines specifically engineered to disrupt the PXK gene, which encodes for a protein involved in various cellular processes, including proliferation, apoptosis, and response to cellular stress. By utilizing CRISPR-Cas9 technology, these knockout cell lines serve as powerful tools for investigating the functional role of the PXK gene in both in vitro and in vivo studies.

The key functions of PXK Gene Knockout Cell Lines revolve around their ability to facilitate targeted gene analysis, enabling researchers to elucidate the cellular pathways regulated by the PXK protein. When the PXK gene is disrupted, researchers can observe the resulting phenotypic changes, thereby providing insights into its role in various biological mechanisms such as tumorigenesis, immune response, and cellular signaling pathways. This can significantly advance our understanding of cancer biology and other diseases associated with PXK dysregulation.

Scientifically, the importance of PXK Gene Knockout Cell Lines lies in their diverse applications in research and clinical settings. They can be leveraged for drug discovery, functional genomics, and studying disease models, ultimately aiding in the development of targeted therapies. The ability to define the specific contributions of the PXK gene could have profound implications for personalized medicine approaches.

Compared to standard cell lines, these genetically modified models offer a unique advantage by providing specific, controlled conditions where the influence of the PXK gene can be accurately assessed. The precise gene knockout minimizes variability often encountered in traditional experimental systems, thereby enhancing the reliability of experimental outcomes.

For researchers and clinicians, the PXK Gene Knockout Cell Lines represent a valuable resource to deepen their understanding of genetic implications in health and disease. By utilizing our product, users can gain deeper insights that could inform not only experimental design but also future therapeutic strategies.

Our company specializes in the development and supply of high-quality biological products tailored to the needs of researchers. With extensive expertise in genetic modification techniques, we are committed to providing advanced tools that support innovative research and contribute to scientific discovery.

Please note that all services are for research use only. Not intended for any clinical use.

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