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PUS7L Knockout Cell Lines

Gene: PUS7L

Official Full Name: pseudouridine synthase 7 likeprovided by HGNC

Gene Summary: Enables pseudouridine synthase activity. Involved in mRNA pseudouridine synthesis. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2025]

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Products Background

Products

Catalog Number Product Name Species Gene Passage ratio Mycoplasma testing Price
KO25505 PUS7L Knockout cell line (HeLa) Human PUS7L 1:3~1:6 Negative Online Inquiry
KO25506 PUS7L Knockout cell line (HCT 116) Human PUS7L 1:2~1:4 Negative Online Inquiry
KO25507 PUS7L Knockout cell line (HEK293) Human PUS7L 1:3~1:6 Negative Online Inquiry
KO25508 PUS7L Knockout cell line (A549) Human PUS7L 1:3~1:4 Negative Online Inquiry

Background

PUS7L Gene Knockout Cell Lines represent a versatile tool in molecular biology, specifically engineered to facilitate the study of the PUS7L gene's functional role in cellular processes. These cell lines are generated using advanced genome editing techniques that introduce targeted disruptions in the PUS7L gene, effectively creating a knockout model. This allows researchers to investigate the gene's functions, interactions, and contributions to various biological pathways.

The primary function of PUS7L involves RNA modification, particularly in the context of pseudouridylation, which is critical for the stability and functionality of various RNA molecules. The knockout of this gene provides a unique mechanism to explore its regulatory effects on RNA metabolism and its implications in processes such as translation, splicing, and overall genome integrity. Researchers can utilize these cell lines to determine the phenotypic outcomes of PUS7L disruption and to elucidate the underlying molecular mechanisms, thereby enhancing our understanding of gene function.

The scientific importance of PUS7L Gene Knockout Cell Lines extends to both basic and applied research. In clinical settings, the insights gained from studying these cell lines could lead to advancements in therapeutic strategies targeting RNA-related diseases. Moreover, understanding the PUS7L gene’s role has potential implications in areas such as cancer research, where RNA modifications are often implicated in tumorigenesis.

What sets PUS7L Gene Knockout Cell Lines apart from alternative models is their specificity and robustness. Unlike conventional gene disruption methods, these cell lines ensure precise targeting without off-target effects, making them invaluable for researchers seeking reliable models to study gene function. The ease of use in experimental setups also facilitates rapid investigation, ultimately enhancing productivity in laboratory settings.

By providing researchers and clinicians with high-quality, well-validated knockout models, PUS7L Gene Knockout Cell Lines stand as a vital resource in the ongoing exploration of gene function and disease mechanisms. Our company is committed to delivering cutting-edge biological products, backed by years of expertise in molecular genetics, ensuring our clients have access to the best tools for their research endeavors.

Please note that all services are for research use only. Not intended for any clinical use.

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