Gene: PUS3
Official Full Name: pseudouridine synthase 3provided by HGNC
Gene Summary: The protein encoded by this gene catalyzes the formation of tRNA pseudouridine from tRNA uridine at position 39 in the anticodon stem and loop of transfer RNAs. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO25471 | PUS3 Knockout cell line (HeLa) | Human | PUS3 | 1:3~1:6 | Negative | Online Inquiry |
KO25472 | PUS3 Knockout cell line (HCT 116) | Human | PUS3 | 1:2~1:4 | Negative | Online Inquiry |
KO25473 | PUS3 Knockout cell line (HEK293) | Human | PUS3 | 1:3~1:6 | Negative | Online Inquiry |
KO25474 | PUS3 Knockout cell line (A549) | Human | PUS3 | 1:3~1:4 | Negative | Online Inquiry |
PUS3 Gene Knockout Cell Lines represent a groundbreaking advancement in genetic research, specifically designed to facilitate studies on the biological roles of the PUS3 gene, which encodes a pivotal enzyme involved in RNA modification and editing. By offering cell lines wherein the PUS3 gene has been effectively disrupted, researchers are equipped with a powerful tool to explore gene function, elucidate molecular pathways, and investigate the downstream effects of altered RNA modifications.
The primary function of these knockout cell lines is to enable the comprehensive analysis of cellular processes influenced by PUS3. Without the presence of this gene, scientists can observe aberrant RNA profiles, changes in translational efficiency, and the overall impact on cell viability and function. Such insights are crucial for understanding the various physiological and pathological roles attributed to RNA modifications in cellular metabolism and disease states.
The scientific importance of PUS3 Gene Knockout Cell Lines is underscored by their potential applications in both research and clinical settings. They serve as a valuable platform for drug discovery, allowing researchers to evaluate the therapeutic effects of compounds targeting RNA modification pathways associated with diseases like cancer and neurodegenerative disorders. Moreover, these cell lines can illuminate the mechanisms behind genetic disorders where RNA editing plays a significant role.
What sets our PUS3 Gene Knockout Cell Lines apart from alternatives on the market is their stringent quality control and validation process, ensuring consistent performance and reproducibility. Each cell line is derived from well-characterized parental cells, allowing for straightforward experimental comparisons. Furthermore, we provide comprehensive user support, including detailed protocols and troubleshooting, which empowers researchers to achieve optimal results in their experiments.
This product holds immense value for researchers focused on genetic and molecular studies, as well as for clinicians exploring novel therapeutic avenues involving RNA modifications. By utilizing PUS3 Gene Knockout Cell Lines, users not only gain insights into fundamental biological processes but also contribute to the delineation of therapeutic strategies for previously intractable diseases.
At our company, we pride ourselves on extensive expertise in the development of advanced biological products, continually striving to support the scientific community with innovative solutions that drive research forward.
Please note that all services are for research use only. Not intended for any clinical use.
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