Gene: PRRX1
Official Full Name: paired related homeobox 1provided by HGNC
Gene Summary: The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription co-activator, enhancing the DNA-binding activity of serum response factor, a protein required for the induction of genes by growth and differentiation factors. The protein regulates muscle creatine kinase, indicating a role in the establishment of diverse mesodermal muscle types. Alternative splicing yields two isoforms that differ in abundance and expression patterns. [provided by RefSeq, Jul 2008]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO01650 | PRRX1 Knockout cell line (HeLa) | Human | PRRX1 | 1:3~1:6 | Negative | Online Inquiry |
PRRX1 Gene Knockout Cell Lines are genetically modified cellular models that have been specifically engineered to lack the PRRX1 gene, which encodes the Paired Related Homeobox 1 protein. This knockout technology allows for the precise study of the biological functions and signaling pathways influenced by PRRX1, a transcription factor implicated in numerous processes, including development, epithelial-mesenchymal transition (EMT), and cancer progression. The removal of this gene facilitates investigations into how its absence affects cellular behavior, signaling cascades, and interactions with various treatments, thereby providing insights into its role in health and disease.
These cell lines function by allowing researchers to observe phenotypic changes resulting from the loss of PRRX1 expression. By utilizing techniques such as CRISPR-Cas9, scientists can create targeted mutations that serve to mimic pathological conditions where PRRX1 might be dysregulated. This is particularly significant in cancer research, as PRRX1 has been associated with metastasis and tumorigenesis, thereby presenting opportunities for therapeutic intervention.
Scientifically, PRRX1 Gene Knockout Cell Lines serve vital roles in both basic and applied research settings, offering a model for examining gene function in a controlled environment. Their applications extend to drug discovery, where understanding the role of PRRX1 can aid in identifying effective treatments for related diseases.
Compared to other gene knockout models, our PRRX1 Gene Knockout Cell Lines stand out due to their high specificity and validation. Each cell line undergoes rigorous characterization to ensure consistent and reproducible results. This level of reliability enhances experimental reproducibility, making our product a preferred choice for researchers seeking to streamline their investigations.
Ultimately, the value of PRRX1 Gene Knockout Cell Lines lies in their ability to facilitate groundbreaking research that can uncover new therapeutic targets and improve our understanding of complex biological systems. By choosing our product, researchers and clinicians gain access to a high-quality resource supported by our company's expertise in genetic engineering and commitment to advancing scientific discovery. Our dedication to providing innovative biological products empowers researchers to push the boundaries of knowledge and enhance health outcomes.
Please note that all services are for research use only. Not intended for any clinical use.
If your question is not addressed through these resources, you can fill out the online form below and we will answer your question as soon as possible.
There is no product in your cart. |
CD Biosynsis is a leading customer-focused biotechnology company dedicated to providing high-quality products, comprehensive service packages, and tailored solutions to support and facilitate the applications of synthetic biology in a wide range of areas.