Gene: PRR12
Official Full Name: proline rich 12provided by HGNC
Gene Summary: This gene encodes a proline-rich protein that contains two A-T hook DNA binding domains. A chromosomal translocation and gene fusion between this gene and zinc finger, MIZ-type containing 1 (Gene ID: 57178) may underlie intellectual disability and neuropsychiatric problems in a human patient. Enriched expression of this gene in embryonic mouse brain suggests that this gene may play a role in nervous system development. [provided by RefSeq, Jul 2016]
Catalog Number | Product Name | Species | Gene | Passage ratio | Mycoplasma testing | Price |
---|---|---|---|---|---|---|
KO14861 | PRR12 Knockout cell line (HeLa) | Human | PRR12 | 1:3~1:6 | Negative | Online Inquiry |
KO14862 | PRR12 Knockout cell line (HCT 116) | Human | PRR12 | 1:2~1:4 | Negative | Online Inquiry |
KO14863 | PRR12 Knockout cell line (HEK293) | Human | PRR12 | 1:3~1:6 | Negative | Online Inquiry |
KO14864 | PRR12 Knockout cell line (A549) | Human | PRR12 | 1:3~1:4 | Negative | Online Inquiry |
PRR12 Gene Knockout Cell Lines are specially engineered cellular models that possess a targeted disruption of the PRR12 gene, which is implicated in several critical biological processes including cell signaling, proliferation, and apoptosis. By omitting this specific gene, these cell lines facilitate the study of PRR12’s role in various cellular functions, thereby offering invaluable insights into its contributions to disease mechanisms and therapeutic interventions.
The primary mechanism of action behind PRR12 Gene Knockout Cell Lines involves the complete abrogation of PRR12 protein expression. This knockout leads to profound phenotypic changes that can be leveraged to study alterations in metabolic pathways, drug responses, and the cellular microenvironment. Such models are vital for elucidating the gene’s involvement in pathological states, including cancer progression and other metabolic disorders.
Scientifically, the PRR12 Gene Knockout Cell Lines represent a significant advancement in molecular biology and biotechnology. They serve as powerful tools in both research and clinical settings by advancing our understanding of gene functions and gene-environment interactions. Researchers can utilize these models to investigate gene therapy strategies, screen for potential drug candidates, and perform detailed mechanistic studies that were previously hindered by the presence of PRR12.
What sets our PRR12 Gene Knockout Cell Lines apart from conventional alternatives is the rigor of our knockout design, which ensures a reliable and reproducible phenotype. Additionally, our lines are thoroughly characterized for specific biological attributes relevant to their application areas, providing scientists with high-quality data for their studies.
The value of the PRR12 Gene Knockout Cell Lines extends beyond mere research; they empower researchers and clinicians to unlock the complexities of gene function and its implications in health and disease. By utilizing these cell lines, users can accelerate discoveries that could lead to the development of novel therapeutics and diagnostic tools tailored to individual patient needs.
Our company prides itself on its expertise in creating genetically modified cell lines and is committed to providing high-quality biological products that support innovative research and clinical applications. We understand the nuances of genetic modifications, and our dedication to scientific excellence ensures that our products meet the highest standards of reliability and performance.
Please note that all services are for research use only. Not intended for any clinical use.
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